百科

9-[2-O-acetyl-3-C-azido-3-deoxy-5-(methylcarbamoyl)-β-D-ribofuranosyl]-2,6-dichloropurine

9-[2-O-acetyl-3-C-azido-3-deoxy-5-(methylcarbamoyl)-β-D-ribofuranosyl]-2,6-dichloropurine

CAS号：786665-97-2

英文名：9-[2-O-acetyl-3-C-azido-3-deoxy-5-(methylcarbamoyl)-β-D-ribofuranosyl]-2,6-dichloropurine

分子式：C13H12Cl2N8O4

分子量：415.192

合成路线

Trifluoro-methanesulfonic acid (3aR,6S,6aR)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

Trifluoro-methanesulfonic acid (3aR,6S,6aR)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

9-[2-O-acetyl-3-C-azido-3-deoxy-5-(methylcarbamoyl)-β-D-ribofuranosyl]-2,6-dichloropurine

9-[2-O-acetyl-3-C-azido-3-deoxy-5-(methylcarbamoyl)-β-D-ribofuranosyl]-2,6-dichloropurine

1,2‑O‑isopropylidene‑3‑azido‑3‑deoxy‑α‑D-ribofuranuronic acid methyl ester

1,2‑O‑isopropylidene‑3‑azido‑3‑deoxy‑α‑D-ribofuranuronic acid methyl ester

9-[2-O-acetyl-3-C-azido-3-deoxy-5-(methylcarbamoyl)-β-D-ribofuranosyl]-2,6-dichloropurine

9-[2-O-acetyl-3-C-azido-3-deoxy-5-(methylcarbamoyl)-β-D-ribofuranosyl]-2,6-dichloropurine

上游原料

1,2‑O‑isopropylidene‑3‑azido‑3‑deoxy‑α‑D-ribofuranuronic acid methyl ester Trifluoro-methanesulfonic acid (3aR,6S,6aR)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

下游产品

(2S,3R,4R,5R)-3-Azido-4-(tert-butyl-dimethyl-silanyloxy)-5-[2-chloro-6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide (2S,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(2-chloro-6-methylamino-purin-9-yl)-3-ureido-tetrahydro-furan-2-carboxylic acid methylamide (2S,3S,4R,5R)-3-Azido-5-(2-chloro-6-methylamino-purin-9-yl)-4-hydroxy-tetrahydro-furan-2-carboxylic acid methylamide (2S,3R,4R,5R)-3-Azido-4-(tert-butyl-dimethyl-silanyloxy)-5-(2-chloro-6-methylamino-purin-9-yl)-tetrahydro-furan-2-carboxylic acid methylamide (2S,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[3-(2-chloro-acetyl)-ureido]-5-(2-chloro-6-methylamino-purin-9-yl)-tetrahydro-furan-2-carboxylic acid methylamide (2S,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-[2-chloro-6-(3-iodo-benzylamino)-purin-9-yl]-3-ureido-tetrahydro-furan-2-carboxylic acid methylamide (2S,3R,4R,5R)-3-Amino-4-(tert-butyl-dimethyl-silanyloxy)-5-(2-chloro-6-methylamino-purin-9-yl)-tetrahydro-furan-2-carboxylic acid methylamide (2S,3R,4R,5R)-3-Amino-4-(tert-butyl-dimethyl-silanyloxy)-5-[2-chloro-6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide (2S,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[3-(2-chloro-acetyl)-ureido]-5-[2-chloro-6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide