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(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

CAS号：78686-70-1

英文名：(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

分子式：C19H36O5Si

分子量：372.572

合成路线

(1S,3R,4R,5S,6S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonane-6,8-diol

(1S,3R,4R,5S,6S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonane-6,8-diol

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(R)-2-[(1S,3R,4R,5S,6S,8S)-8-Benzyloxy-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]non-3-yl]-propan-1-ol

(R)-2-[(1S,3R,4R,5S,6S,8S)-8-Benzyloxy-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]non-3-yl]-propan-1-ol

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,6S)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-one

(1S,3R,4R,5S,6S)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

{(R)-2-[(1S,3R,4R,5S,6S,8S)-8-Benzyloxy-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]non-3-yl]-propoxy}-tert-butyl-dimethyl-silane

{(R)-2-[(1S,3R,4R,5S,6S,8S)-8-Benzyloxy-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]non-3-yl]-propoxy}-tert-butyl-dimethyl-silane

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(2R,3R,4R)-4-[(2S,3S,5S,6R)-5-Benzyloxy-6-methoxy-3-(2-methoxy-ethoxymethoxy)-6-methyl-tetrahydro-pyran-2-yl]-2-methyl-pentane-1,3-diol

(2R,3R,4R)-4-[(2S,3S,5S,6R)-5-Benzyloxy-6-methoxy-3-(2-methoxy-ethoxymethoxy)-6-methyl-tetrahydro-pyran-2-yl]-2-methyl-pentane-1,3-diol

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

((2R,3R)-3-{(R)-1-[(2S,3S,5S,6R)-5-Benzyloxy-6-methoxy-3-(2-methoxy-ethoxymethoxy)-6-methyl-tetrahydro-pyran-2-yl]-ethyl}-oxiranyl)-methanol

((2R,3R)-3-{(R)-1-[(2S,3S,5S,6R)-5-Benzyloxy-6-methoxy-3-(2-methoxy-ethoxymethoxy)-6-methyl-tetrahydro-pyran-2-yl]-ethyl}-oxiranyl)-methanol

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,6S,8S)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-ol

(1S,3R,4R,5S,6S,8S)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-ol

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,6S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-ol

(1S,3R,4R,5S,6S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-ol

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

(1S,3R,4R,5S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-8-hydroxy-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-6-one

上游原料

(1S,3R,4R,5S,6S)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-one (1S,3R,4R,5S,6S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-ol {(R)-2-[(1S,3R,4R,5S,6S,8S)-8-Benzyloxy-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]non-3-yl]-propoxy}-tert-butyl-dimethyl-silane (1S,3R,4R,5S,6S,8S)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]nonan-8-ol (2R,3R,4R)-4-[(2S,3S,5S,6R)-5-Benzyloxy-6-methoxy-3-(2-methoxy-ethoxymethoxy)-6-methyl-tetrahydro-pyran-2-yl]-2-methyl-pentane-1,3-diol (R)-2-[(1S,3R,4R,5S,6S,8S)-8-Benzyloxy-6-(2-methoxy-ethoxymethoxy)-1,4-dimethyl-2,9-dioxa-bicyclo[3.3.1]non-3-yl]-propan-1-ol (1S,3R,4R,5S,6S,8R)-3-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]nonane-6,8-diol ((2R,3R)-3-{(R)-1-[(2S,3S,5S,6R)-5-Benzyloxy-6-methoxy-3-(2-methoxy-ethoxymethoxy)-6-methyl-tetrahydro-pyran-2-yl]-ethyl}-oxiranyl)-methanol

下游产品

(1S,3R,4R,5S)-3-((R)-2-Hydroxy-1-methyl-ethyl)-1,4,8-trimethyl-2,9-dioxa-bicyclo[3.3.1]non-7-en-6-one (S)-2-((1S,3S,4R,5S)-1,4,8-Trimethyl-6-oxo-2,9-dioxa-bicyclo[3.3.1]non-7-en-3-yl)-propionaldehyde