百科

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

CAS号：81165-08-4

英文名：(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

分子式：C17H19NO3

分子量：285.338

合成路线

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-9-((1-phenyl-1H-tetrazol-5-yl)oxy)-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-9-((1-phenyl-1H-tetrazol-5-yl)oxy)-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

3-O-[(trifluoromethyl)sulfonyl]oripavine

3-O-[(trifluoromethyl)sulfonyl]oripavine

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

3-deoxyoripavine

3-deoxyoripavine

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

(4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

上游原料

3-deoxyoripavine (4R,4aS,7aR,12bS)-4a-hydroxy-3-methyl-9-((1-phenyl-1H-tetrazol-5-yl)oxy)-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one 3-O-[(trifluoromethyl)sulfonyl]oripavine

下游产品

(-)-14-hydroxy-4-methoxymorphinan-6-one (-)-4-methoxy-14-hydroxy-6-keto-N-methylmorphinan 2,2,2-trichloroethyl (4bR,8aS,9R)-4-methoxy-6-oxo-8a-(((2,2,2-trichloroethoxy)carbonyl)oxy)-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carboxylate (-)-4,14-dimethoxy-N-methylmorphinan-6-one (-)-14-methoxy-N-methyl-4-<(1-phenyl-1H-tetrazol-5-yl)oxy>morphinan-6-one (-)-4,5α-epoxy-14-methoxy-N-methylmorphinan-6-one (-)-4-methoxy-14-hydroxy-6-keto-N-cyclopropylcarbonylmorphinan