[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

CAS号：81378-61-2

英文名：[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

分子式：C36H42N6O9

分子量：702.753

合成路线

ethyl D-alanylglycinate

ethyl D-alanylglycinate

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

66450-33-7

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

Z-Tyr-D-Ala-Gly-OEt

Z-Tyr-D-Ala-Gly-OEt

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

Z-Tyr-D-Ala-Gly-Phe-NHNH-Boc

Z-Tyr-D-Ala-Gly-Phe-NHNH-Boc

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

Z-Tyr-ONB

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

[(S)-1-{(R)-1-[({(S)-1-Benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

上游原料

Z-Tyr-ONB Z-Tyr-D-Ala-Gly-Phe-NHNH-Boc Z-Tyr-D-Ala-Gly-OEt ethyl D-alanylglycinate

下游产品

(S)-2-Amino-N-{(R)-1-[({(S)-1-benzyl-2-oxo-2-[N'-(4-oxo-pentanoyl)-hydrazino]-ethylcarbamoyl}-methyl)-carbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide