百科

Thiophene-2-sulfonic acid {3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-ethyl]-phenyl}-amide

Thiophene-2-sulfonic acid {3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-ethyl]-phenyl}-amide

CAS号：820216-51-1

英文名：Thiophene-2-sulfonic acid {3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-ethyl]-phenyl}-amide

分子式：C39H46N4O6S2Si

分子量：759.021

合成路线

(R)-3-(2-aminopropyl)-7-benzyloxyindole

(R)-3-(2-aminopropyl)-7-benzyloxyindole

Thiophene-2-sulfonic acid {3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-ethyl]-phenyl}-amide

Thiophene-2-sulfonic acid {3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-ethyl]-phenyl}-amide

(2R)-7-benzyloxy-3-[2-(tert-butoxycarbonylamino)propyl]-1H-indole

(2R)-7-benzyloxy-3-[2-(tert-butoxycarbonylamino)propyl]-1H-indole

Thiophene-2-sulfonic acid {3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-ethyl]-phenyl}-amide

Thiophene-2-sulfonic acid {3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-ethyl]-phenyl}-amide

上游原料

(2R)-7-benzyloxy-3-[2-(tert-butoxycarbonylamino)propyl]-1H-indole (R)-3-(2-aminopropyl)-7-benzyloxyindole

下游产品

Thiophene-2-sulfonic acid {3-[(R)-2-((R)-2-{7-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-1H-indol-3-yl}-1-methyl-ethylamino)-1-hydroxy-ethyl]-phenyl}-amide