百科

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

CAS号：828914-62-1

英文名：(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

分子式：C18H25N5O7

分子量：423.42

合成路线

(1'R,2R,3R,4S,5S)-4-azido-2-(1'-hydroxy-2',2'-bis-phenylsulfanylethyl)-5-methoxy-tetrahydropyran-3-ol

(1'R,2R,3R,4S,5S)-4-azido-2-(1'-hydroxy-2',2'-bis-phenylsulfanylethyl)-5-methoxy-tetrahydropyran-3-ol

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(4R,4aR,7S,8R,8aR)-8-Azido-4-(bis-phenylsulfanyl-methyl)-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

(4R,4aR,7S,8R,8aR)-8-Azido-4-(bis-phenylsulfanyl-methyl)-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,7S,7aR)-7-Azido-3-benzyloxy-2-methoxy-tetrahydro-furo[3,2-b]pyran-6-one

(2R,3R,3aR,7S,7aR)-7-Azido-3-benzyloxy-2-methoxy-tetrahydro-furo[3,2-b]pyran-6-one

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,7aR)-3-benzyloxy-2-methoxy-3,3a,5,7a-tetrahydro-2H-furo[3,2-b]pyran

(2R,3R,3aR,7aR)-3-benzyloxy-2-methoxy-3,3a,5,7a-tetrahydro-2H-furo[3,2-b]pyran

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

methyl 3-O-allyl-5,6-dideoxy-β-D-ribo-hex-5-enofuranoside

methyl 3-O-allyl-5,6-dideoxy-β-D-ribo-hex-5-enofuranoside

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

(2R,3R,3aR,6S,7R,7aR)-7-azido-2-(5'-methyl-2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran

上游原料

(2R,3R,3aR,7S,7aR)-7-Azido-3-benzyloxy-2-methoxy-tetrahydro-furo[3,2-b]pyran-6-one methyl 3-O-allyl-5,6-dideoxy-β-D-ribo-hex-5-enofuranoside (4R,4aR,7S,8R,8aR)-8-Azido-4-(bis-phenylsulfanyl-methyl)-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol (1'R,2R,3R,4S,5S)-4-azido-2-(1'-hydroxy-2',2'-bis-phenylsulfanylethyl)-5-methoxy-tetrahydropyran-3-ol (2R,3R,3aR,7aR)-3-benzyloxy-2-methoxy-3,3a,5,7a-tetrahydro-2H-furo[3,2-b]pyran

下游产品

2,2-Dimethyl-propionic acid (2R,3R,3aR,6S,7R,7aR)-6-methoxy-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-7-[3-(2,2,2-trichloro-acetyl)-ureido]-hexahydro-furo[3,2-b]pyran-3-yl ester