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7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

CAS号：84338-99-8

英文名：7-fluoro-5-oxo-8-piperazin-1-yl-[1,3]thiazolo[3,2-a]quinoline-4-carboxylic acid

分子式：C16H14FN3O3S

分子量：347.364

合成路线

碳酸钾

8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylic acid

8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylic acid

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

3-氯-4-氟苯胺

3-氯-4-氟苯胺

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

3-氯-4-氟苯基异硫氰酸酯

3-氯-4-氟苯基异硫氰酸酯

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

ethyl 7-chloro-6-fluoro-4-hydroxy-2-mercaptoquinoline-3-carboxylate

ethyl 7-chloro-6-fluoro-4-hydroxy-2-mercaptoquinoline-3-carboxylate

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

ethyl 8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylate

ethyl 8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylate

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

ethyl 7-chloro-6-fluoro-4-hydroxy-2-(p-methoxybenzylthio)quinoline-3-carboxylate

ethyl 7-chloro-6-fluoro-4-hydroxy-2-(p-methoxybenzylthio)quinoline-3-carboxylate

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

diethyl (3-chloro-4-fluorophenyl)amino(4-methoxybenzyl)-thiomethylenemalonate

diethyl (3-chloro-4-fluorophenyl)amino(4-methoxybenzyl)-thiomethylenemalonate

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

Sodium; 1-(3-chloro-4-fluoro-phenylamino)-2,2-bis-ethoxycarbonyl-ethenethiolate

Sodium; 1-(3-chloro-4-fluoro-phenylamino)-2,2-bis-ethoxycarbonyl-ethenethiolate

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylic acid

8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylic acid

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

7-氟-5-氧代-8-(1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸

上游原料

diethyl (3-chloro-4-fluorophenyl)amino(4-methoxybenzyl)-thiomethylenemalonate 3-氯-4-氟苯基异硫氰酸酯 Sodium; 1-(3-chloro-4-fluoro-phenylamino)-2,2-bis-ethoxycarbonyl-ethenethiolate 碳酸钾 3-氯-4-氟苯胺哌嗪 ethyl 7-chloro-6-fluoro-4-hydroxy-2-mercaptoquinoline-3-carboxylate ethyl 8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylate ethyl 7-chloro-6-fluoro-4-hydroxy-2-(p-methoxybenzylthio)quinoline-3-carboxylate 8-chloro-7-fluoro-5-oxo-5H-thiazolo[3,2-a]quinoline-4-carboxylic acid

下游产品

7-氟-5-氧代-8-(4-(2-丙烯基)-1-哌嗪基)-5H-噻唑并[3,2-a]喹啉-4-羧酸