百科

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

CAS号：848565-35-5

英文名：4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

分子式：C30H46O7

分子量：518.682

合成路线

((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-methanol

((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-methanol

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxy)-tert-butyl-dimethyl-silane

((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxy)-tert-butyl-dimethyl-silane

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl)-benzoic acid (2R,3R,5S,6S)-3-but-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethyl ester

4-((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl)-benzoic acid (2R,3R,5S,6S)-3-but-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-((2R,3S,5S,6S)-3-Formyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid

4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-((2R,3S,5S,6S)-3-Formyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-((2R,3R,5S,6S)-3-Hydroxymethyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid

4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-((2R,3R,5S,6S)-3-Hydroxymethyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-[(2R,3R,5S,6S)-3-((Z)-Dec-1-enyl)-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl]-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid

4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-[(2R,3R,5S,6S)-3-((Z)-Dec-1-enyl)-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl]-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

4-{(R)-2-Hydroxy-2-[(2R,5R,2'R,5'R)-5'-((Z)-(R)-1-hydroxy-undec-2-enyl)-octahydro-[2,2']bifuranyl-5-yl]-ethoxymethyl}-benzoic acid methyl ester

上游原料

4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-((2R,3R,5S,6S)-3-Hydroxymethyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid 4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-((2R,3S,5S,6S)-3-Formyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid ((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxy)-tert-butyl-dimethyl-silane 4-((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl)-benzoic acid (2R,3R,5S,6S)-3-but-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethyl ester 4-{(2R,3R,5S,6S)-3-[(3S,4S)-6-[(2R,3R,5S,6S)-3-((Z)-Dec-1-enyl)-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl]-3,4-bis-(toluene-4-sulfonyloxy)-hexyl]-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxymethyl}-benzoic acid ((2R,3R,5S,6S)-3-But-3-enyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-yl)-methanol

下游产品

(S)-3-{(2R,8R,13R)-8-Hydroxy-2,13-bis-methoxymethoxy-13-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-tridecyl}-5-methyl-5H-furan-2-one (R)-6-Methoxymethoxy-6-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-hexanoic acid methoxy-methyl-amide (2E,4E)-(R)-6-Methoxymethoxy-6-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-hexa-2,4-dienoic acid ethyl ester (R)-2-Methoxymethoxy-2-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-ethanol (R)-6-Methoxymethoxy-6-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-hexanoic acid ethyl ester (S)-Methoxymethoxy-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-acetaldehyde (R)-8-Methoxymethoxy-8-[(2R,5R,2'R,5'R)-5'-((R)-1-methoxymethoxy-undecyl)-octahydro-[2,2']bifuranyl-5-yl]-oct-1-yn-3-one