百科

3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

CAS号：849204-08-6

英文名：3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

分子式：C27H36FN3O

分子量：437.593

合成路线

1-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-methylene-2-(S)-(3-fluorophenyl)cyclopentane

1-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-methylene-2-(S)-(3-fluorophenyl)cyclopentane

3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

(3S,4S)-3-((R)-1-(1,3-diethyl-4,5-dihydro-1H-spiro[cyclopenta[c]pyrazole-6,4'-piperidin]-1'-yl)ethyl)-4-(3-fluorophenyl)-1-(hydroxymethyl)cyclopentan-1-ol

(3S,4S)-3-((R)-1-(1,3-diethyl-4,5-dihydro-1H-spiro[cyclopenta[c]pyrazole-6,4'-piperidin]-1'-yl)ethyl)-4-(3-fluorophenyl)-1-(hydroxymethyl)cyclopentan-1-ol

3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

上游原料

1-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-methylene-2-(S)-(3-fluorophenyl)cyclopentane (3S,4S)-3-((R)-1-(1,3-diethyl-4,5-dihydro-1H-spiro[cyclopenta[c]pyrazole-6,4'-piperidin]-1'-yl)ethyl)-4-(3-fluorophenyl)-1-(hydroxymethyl)cyclopentan-1-ol

下游产品

tert-butyl ((3S,4S)-3-((R)-1-(1,3-diethyl-4,5-dihydro-1H-spiro[cyclopenta[c]pyrazole-6,4'-piperidin]-1'-yl)ethyl)-4-(3-fluorophenyl)cyclopentyl)-D-valinate