百科

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

CAS号：849482-41-3

英文名：(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

分子式：C29H42O8

分子量：518.639

合成路线

(S)-2-{(2S,5R)-5-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-propyl]-tetrahydro-furan-2-yl}-propionic acid (1R,3R)-3-benzyloxymethoxy-1-vinyl-pentyl ester

(S)-2-{(2S,5R)-5-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-propyl]-tetrahydro-furan-2-yl}-propionic acid (1R,3R)-3-benzyloxymethoxy-1-vinyl-pentyl ester

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(S)-2-[(2S,5R)-5-((S)-2-Benzyloxy-propyl)-tetrahydro-furan-2-yl]-propionic acid methyl ester

(S)-2-[(2S,5R)-5-((S)-2-Benzyloxy-propyl)-tetrahydro-furan-2-yl]-propionic acid methyl ester

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(3R,5R)-5-Benzyloxymethoxy-hept-1-en-3-ol

(3R,5R)-5-Benzyloxymethoxy-hept-1-en-3-ol

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(R)-3-Benzyloxymethoxy-pentanoic acid methyl ester

(R)-3-Benzyloxymethoxy-pentanoic acid methyl ester

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(E)-3-[(1S,3S)-3-Benzyloxy-1-(2-iodo-ethyl)-butoxy]-2-methyl-acrylic acid methyl ester

(E)-3-[(1S,3S)-3-Benzyloxy-1-(2-iodo-ethyl)-butoxy]-2-methyl-acrylic acid methyl ester

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

(E)-(1S,2S,5R,8R,9R,12S,14R)-5-((R)-2-Benzyloxymethoxy-butyl)-8-hydroxy-2,9,12-trimethyl-4,11,17-trioxa-bicyclo[12.2.1]heptadec-6-ene-3,10-dione

上游原料

(S)-2-{(2S,5R)-5-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-propyl]-tetrahydro-furan-2-yl}-propionic acid (1R,3R)-3-benzyloxymethoxy-1-vinyl-pentyl ester (S)-2-[(2S,5R)-5-((S)-2-Benzyloxy-propyl)-tetrahydro-furan-2-yl]-propionic acid methyl ester (3R,5R)-5-Benzyloxymethoxy-hept-1-en-3-ol (E)-3-[(1S,3S)-3-Benzyloxy-1-(2-iodo-ethyl)-butoxy]-2-methyl-acrylic acid methyl ester (R)-3-Benzyloxymethoxy-pentanoic acid methyl ester

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