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(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

CAS号：851889-73-1

英文名：(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

分子式：C36H60O6Si2

分子量：645.029

合成路线

851889-68-4

(3E,5S,6S,7R)-6,8-[(R)-4-methoxy-benzylidenedioxy]-4,5,7-trimethyl-oct-3-enoic acid methyl ester

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

444109-28-8

(3S,4R,5S)-6-benzyloxy-4-(tert-butyldimethylsilanyloxy)-3,5-dimethyltrimethylsilanylhex-1-yne

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

444109-29-9

(1E,3S,4R,5S)-6-benzyloxy-4-(tert-butyldimethylsilanyloxy)-3,5-dimethyl-1-iodo-1-trimethylsilanyl-hex-1-ene

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

444109-24-4

(3E,5S,6S,7R)-6,8-dihydroxy-4,5,7-trimethyl-oct-3-enonic acid methyl ester

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

444109-43-7

(Z)-(2R,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-6-trimethylsilanyl-hept-5-enal

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

444109-31-3

(2S,3R,4S,5Z)-3-(tert-butyldimethylsilanyloxy)-2,4-dimethyl-6-trimethylsilanyl-5-en-1-ol

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

444109-32-4

(3S,4R,5S,6Z)-1,1-dibromo-4-(tert-butyldimethylsilanyloxy)-3,5-trimethyl-7-trimethylsilanyl-octa-1,6-diene

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

444109-26-6

(3E,5S,6R,7S)-8-benzyloxy-6-(tert-butyldimethylsilanyloxy)-5,7-dimethyl-oct-3-enoic acid methyl ester

851889-73-1

(2S,3R,4R,7S,10S,11R,12S,13Z)-11-(tert-butyldimethylsilanyloxy)-1,3-[(R)-4-methoxybenzylidenedioxy]-7-hydroxy-2,4,10,12-tetramethyl-14-trimethylsilanylpentadec-13-en-8-yn-5-one

上游原料

(3E,5S,6S,7R)-6,8-dihydroxy-4,5,7-trimethyl-oct-3-enonic acid methyl ester (Z)-(2R,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-6-trimethylsilanyl-hept-5-enal (3E,5S,6R,7S)-8-benzyloxy-6-(tert-butyldimethylsilanyloxy)-5,7-dimethyl-oct-3-enoic acid methyl ester (3S,4R,5S)-6-benzyloxy-4-(tert-butyldimethylsilanyloxy)-3,5-dimethyltrimethylsilanylhex-1-yne (3E,5S,6S,7R)-6,8-[(R)-4-methoxy-benzylidenedioxy]-4,5,7-trimethyl-oct-3-enoic acid methyl ester (1E,3S,4R,5S)-6-benzyloxy-4-(tert-butyldimethylsilanyloxy)-3,5-dimethyl-1-iodo-1-trimethylsilanyl-hex-1-ene (2S,3R,4S,5Z)-3-(tert-butyldimethylsilanyloxy)-2,4-dimethyl-6-trimethylsilanyl-5-en-1-ol (3S,4R,5S,6Z)-1,1-dibromo-4-(tert-butyldimethylsilanyloxy)-3,5-trimethyl-7-trimethylsilanyl-octa-1,6-diene

下游产品

(Z)-(2S,3S,5S,8S,9R,10S)-9-(tert-Butyl-dimethyl-silanyloxy)-2-[(2R,4R,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-8,10-dimethyl-12-trimethylsilanyl-tridec-11-en-6-yne-3,5-diol