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3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

CAS号：860651-70-3

英文名：3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

分子式：C33H38N2O5Si

分子量：570.751

合成路线

((3aR,5R,6S,6aR)-6-Benzyloxy-5-iodomethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-diphenyl-silane

((3aR,5R,6S,6aR)-6-Benzyloxy-5-iodomethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-diphenyl-silane

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

3-O-benzyl-5-O-tert-butyldiphenylsilyl-4-C-methyl-1,2-O-isopropylidene-α-D-ribofuranose

3-O-benzyl-5-O-tert-butyldiphenylsilyl-4-C-methyl-1,2-O-isopropylidene-α-D-ribofuranose

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

2'-O-acetyl-3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-4'-C-methyluridine

2'-O-acetyl-3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-4'-C-methyluridine

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

1,2-di-O-acetyl-3-O-benzyl-5-O-tert-butyldiphenylsilyl-4-C-methyl-α,β-D-ribofuranose

1,2-di-O-acetyl-3-O-benzyl-5-O-tert-butyldiphenylsilyl-4-C-methyl-α,β-D-ribofuranose

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

{3-[(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)methyl]-(1S,3R,4S,5R)-7,7-dimethyl-2,6,8-trioxa-4-(phenylmethoxy)bicyclo[3.3.0]oct-3-yl}methan-1-ol

{3-[(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)methyl]-(1S,3R,4S,5R)-7,7-dimethyl-2,6,8-trioxa-4-(phenylmethoxy)bicyclo[3.3.0]oct-3-yl}methan-1-ol

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-4'-C-methyluridine

上游原料

1,2-di-O-acetyl-3-O-benzyl-5-O-tert-butyldiphenylsilyl-4-C-methyl-α,β-D-ribofuranose 3-O-benzyl-5-O-tert-butyldiphenylsilyl-4-C-methyl-1,2-O-isopropylidene-α-D-ribofuranose ((3aR,5R,6S,6aR)-6-Benzyloxy-5-iodomethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-diphenyl-silane {3-[(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)methyl]-(1S,3R,4S,5R)-7,7-dimethyl-2,6,8-trioxa-4-(phenylmethoxy)bicyclo[3.3.0]oct-3-yl}methan-1-ol 2'-O-acetyl-3'-O-benzyl-5'-O-tert-butyldiphenylsilyl-4'-C-methyluridine

下游产品

2'-deoxy-5'-O-dimethoxytrityl-4'-C-methyluridine 2′-deoxy-4′-propyluridine