百科

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

CAS号：864238-70-0

英文名：(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

分子式：C27H46Cl3N3O7S

分子量：663.094

合成路线

864238-67-5

(4S,5S)-4-Isobutyl-2,2-dimethyl-5-{(1R,2R)-2-[(S)-1-(2,2,2-trichloro-ethoxycarbonyl)-ethylcarbamoyl]-cyclopentyl}-oxazolidine-3-carboxylic acid tert-butyl ester

864238-70-0

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

864239-02-1

tert-butyl (4S,5S)-4-isobutyl-5-((1R,2R)-2-(methoxycarbonyl)-4-(2-tosylhydrazineylidene)cyclopentyl)-2,2-dimethyloxazolidine-3-carboxylate

864238-70-0

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

864238-49-3

(4S)-isobutyl-(5S)-(2-methoxycarbonyl-vinyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864238-70-0

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

864238-51-7

(4S)-isobutyl-(5S)-((2R)-methoxycarbonyl-4-oxo-cyclopentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864238-70-0

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

864238-48-2

(4S,5S)-isobutyl-5-methoxycarbonylethynyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864238-70-0

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

864238-52-8

(4S)-isobutyl-(5S)-((2R)-methoxycarbonyl-cyclopentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864238-70-0

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

864238-50-6

(4S)-isobutyl-(5S)-((2R)-methoxycarbonyl-4-methylenecyclopentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864238-70-0

(S)-2-({(1R,2R)-2-[(1S,2S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-1-hydroxy-4-methyl-pentyl]-cyclopentanecarbonyl}-amino)-propionic acid 2,2,2-trichloro-ethyl ester

上游原料

(4S)-isobutyl-(5S)-(2-methoxycarbonyl-vinyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (4S)-isobutyl-(5S)-((2R)-methoxycarbonyl-cyclopentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (4S,5S)-4-Isobutyl-2,2-dimethyl-5-{(1R,2R)-2-[(S)-1-(2,2,2-trichloro-ethoxycarbonyl)-ethylcarbamoyl]-cyclopentyl}-oxazolidine-3-carboxylic acid tert-butyl ester (4S,5S)-isobutyl-5-methoxycarbonylethynyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (4S)-isobutyl-(5S)-((2R)-methoxycarbonyl-4-oxo-cyclopentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (4S)-isobutyl-(5S)-((2R)-methoxycarbonyl-4-methylenecyclopentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester tert-butyl (4S,5S)-4-isobutyl-5-((1R,2R)-2-(methoxycarbonyl)-4-(2-tosylhydrazineylidene)cyclopentyl)-2,2-dimethyloxazolidine-3-carboxylate

下游产品

(S)-2-[((1R,2R)-2-{(1S,2S)-2-[(S)-2-((S)-2-Acetylamino-4-methyl-pentanoylamino)-4-methylsulfanyl-butyrylamino]-1-hydroxy-4-methyl-pentyl}-cyclopentanecarbonyl)-amino]-propionic acid 2,2,2-trichloro-ethyl ester