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(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

CAS号：864239-15-6

英文名：(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

分子式：C29H52N4O6

分子量：552.746

合成路线

864852-81-3

(4S)-isobutyl-(5S)-(2-methoxycarbonyl-1-methyl-5-oxo-4-(toluene-4-sulfonyl)-pyrrolidin-3-yl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864239-15-6

(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

728947-30-6

(5S)-tert-butoxycarbonylamino-(4S,R)-hydroxy-7-methyl-oct-2-ynoic acid methyl ester

864239-15-6

(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864238-49-3

(4S)-isobutyl-(5S)-(2-methoxycarbonyl-vinyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864239-15-6

(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864764-46-5

(5S)-((Z)-2-bromo-2-methoxycarbonyl-vinyl)-(4S)-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864239-15-6

(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864238-48-2

(4S,5S)-isobutyl-5-methoxycarbonylethynyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864239-15-6

(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

107599-97-3

(5R)-formyl-(4S)-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

864239-15-6

(4S,5S)-5-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

上游原料

(4S)-isobutyl-(5S)-(2-methoxycarbonyl-vinyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (5S)-tert-butoxycarbonylamino-(4S,R)-hydroxy-7-methyl-oct-2-ynoic acid methyl ester (4S)-isobutyl-(5S)-(2-methoxycarbonyl-1-methyl-5-oxo-4-(toluene-4-sulfonyl)-pyrrolidin-3-yl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (5S)-((Z)-2-bromo-2-methoxycarbonyl-vinyl)-(4S)-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (4S,5S)-isobutyl-5-methoxycarbonylethynyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (5R)-formyl-(4S)-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

下游产品

[(S)-1-((S)-1-{(S)-[(2R,3R)-2-((S)-1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-methyl-5-oxo-pyrrolidin-3-yl]-hydroxy-methyl}-3-methyl-butylcarbamoyl)-3-methylsulfanyl-propyl]-carbamic acid tert-butyl ester