百科

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

CAS号：864366-88-1

英文名：(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

分子式：C20H37N3O6

分子量：415.524

合成路线

(3S)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one

(3S)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3R)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one

(3R)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carbaldehyde

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carbaldehyde

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-dihydro-furan-2-one

(3S)-3-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-dihydro-furan-2-one

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid methyl ester

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid methyl ester

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(S)-dibenzyl-[(3S)-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-(2-[1,3]dithian-2-yl-tetrahydrofuran-3-yl)-methyl]-3-methyl-butyl]-amine

(S)-dibenzyl-[(3S)-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-(2-[1,3]dithian-2-yl-tetrahydrofuran-3-yl)-methyl]-3-methyl-butyl]-amine

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(2S)-2-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-(1S)-1-[1,3]dithian-2-yl-butane-1,4-diol

(2S)-2-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-(1S)-1-[1,3]dithian-2-yl-butane-1,4-diol

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

(3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide

上游原料

(3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid N-methyl-L-alanine amide (3S)-3-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-dihydro-furan-2-one (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid (2S)-2-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-(1S)-1-[1,3]dithian-2-yl-butane-1,4-diol (S)-dibenzyl-[(3S)-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-(2-[1,3]dithian-2-yl-tetrahydrofuran-3-yl)-methyl]-3-methyl-butyl]-amine (3R)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carbaldehyde (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid methyl ester (3S)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid

下游产品

[(S)-1-((S)-1-{(S)-Hydroxy-[(2R,3S)-2-((S)-1-methylcarbamoyl-ethylcarbamoyl)-tetrahydro-furan-3-yl]-methyl}-3-methyl-butylcarbamoyl)-2-(trityl-carbamoyl)-ethyl]-carbamic acid tert-butyl ester