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(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

CAS号：865535-41-7

英文名：(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

分子式：C34H56N2O5Si

分子量：600.904

合成路线

865535-39-3

(Z)-(S)-1-(1,2-Dimethyl-1H-benzoimidazol-5-yl)-4-iodo-but-3-en-1-ol

865535-41-7

(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

865535-32-6

(6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-4,4,6,8-tetramethyl-5-oxo-undec-10-enoic acid methyl ester

865535-41-7

(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

865535-30-4

(E)-(6R,7S,8S)-11-Benzyloxy-7-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8-tetramethyl-5-oxo-undec-2-enoic acid methyl ester

865535-41-7

(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

279227-20-2

(2S)-5-benzyloxy-2-methyl-1-pentanal

865535-41-7

(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

865535-29-1

(E)-(6R,7S,8S)-11-Benzyloxy-7-hydroxy-4,4,6,8-tetramethyl-5-oxo-undec-2-enoic acid methyl ester

865535-41-7

(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

865535-31-5

(6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-11-hydroxy-4,4,6,8-tetramethyl-5-oxo-undecanoic acid methyl ester

865535-41-7

(Z)-(6R,7S,8S,15S)-7-(tert-Butyl-dimethyl-silanyloxy)-15-(1,2-dimethyl-1H-benzoimidazol-5-yl)-15-hydroxy-4,4,6,8-tetramethyl-5-oxo-pentadec-12-enoic acid

上游原料

(2S)-5-benzyloxy-2-methyl-1-pentanal (Z)-(S)-1-(1,2-Dimethyl-1H-benzoimidazol-5-yl)-4-iodo-but-3-en-1-ol (E)-(6R,7S,8S)-11-Benzyloxy-7-hydroxy-4,4,6,8-tetramethyl-5-oxo-undec-2-enoic acid methyl ester (6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-4,4,6,8-tetramethyl-5-oxo-undec-10-enoic acid methyl ester (6R,7S,8S)-7-(tert-Butyl-dimethyl-silanyloxy)-11-hydroxy-4,4,6,8-tetramethyl-5-oxo-undecanoic acid methyl ester (E)-(6R,7S,8S)-11-Benzyloxy-7-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8-tetramethyl-5-oxo-undec-2-enoic acid methyl ester

下游产品

(Z)-(7R,8S,9S,16S)-8-(tert-Butyl-dimethyl-silanyloxy)-16-(1,2-dimethyl-1H-benzoimidazol-5-yl)-5,5,7,9-tetramethyl-oxacyclohexadec-13-ene-2,6-dione