百科

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

CAS号：866138-95-6

英文名：ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

分子式：C39H62O6Si2

分子量：683.077

合成路线

(R)-5-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-(tert-butyl-dimethyl-silanyloxy)-5-oxo-pentanal

(R)-5-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-(tert-butyl-dimethyl-silanyloxy)-5-oxo-pentanal

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

(4S,6E)-4-tert-butyldiphenylsilyloxy-6-octen-1-ol

(4S,6E)-4-tert-butyldiphenylsilyloxy-6-octen-1-ol

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

(tert-butyl)(dimethyl){3-[(2S)-oxiran-2-yl]propoxy}silane

(tert-butyl)(dimethyl){3-[(2S)-oxiran-2-yl]propoxy}silane

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

ethyl (2E,4R,6S,7S,10S,12E)-4-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-7-hydroxy-6-(hydroxymethyl)tetradeca-2,12-dienoate

上游原料

(R)-5-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-(tert-butyl-dimethyl-silanyloxy)-5-oxo-pentanal (4S,6E)-4-tert-butyldiphenylsilyloxy-6-octen-1-ol (tert-butyl)(dimethyl){3-[(2S)-oxiran-2-yl]propoxy}silane

下游产品

(2E,12E)-(4R,6R,7S,10S)-4-(tert-Butyl-dimethyl-silanyloxy)-10-(tert-butyl-diphenyl-silanyloxy)-7-methanesulfonyloxy-6-(pyridin-2-ylselanylmethyl)-tetradeca-2,12-dienoic acid ethyl ester