百科

(8S,10R,12S,15R)-15-((R)-4-Hydroxy-3-methyl-2-methylene-butyl)-10-(4-methoxy-benzyloxymethyl)-9,14-dioxa-1,5-dithia-dispiro[5.1.5.3]hexadecan-12-ol

(8S,10R,12S,15R)-15-((R)-4-Hydroxy-3-methyl-2-methylene-butyl)-10-(4-methoxy-benzyloxymethyl)-9,14-dioxa-1,5-dithia-dispiro[5.1.5.3]hexadecan-12-ol

CAS号：868266-91-5

英文名：(8S,10R,12S,15R)-15-((R)-4-Hydroxy-3-methyl-2-methylene-butyl)-10-(4-methoxy-benzyloxymethyl)-9,14-dioxa-1,5-dithia-dispiro[5.1.5.3]hexadecan-12-ol

分子式：C27H40O6S2

分子量：524.733

合成路线

1-[(4S,6R)-6-(4-Methoxy-benzyloxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-3-[2-((R)-5-methyl-4-methylene-2,6-bis-triethylsilanyloxy-hexyl)-[1,3]dithian-2-yl]-propan-2-one

1-[(4S,6R)-6-(4-Methoxy-benzyloxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-3-[2-((R)-5-methyl-4-methylene-2,6-bis-triethylsilanyloxy-hexyl)-[1,3]dithian-2-yl]-propan-2-one

(8S,10R,12S,15R)-15-((R)-4-Hydroxy-3-methyl-2-methylene-butyl)-10-(4-methoxy-benzyloxymethyl)-9,14-dioxa-1,5-dithia-dispiro[5.1.5.3]hexadecan-12-ol

(8S,10R,12S,15R)-15-((R)-4-Hydroxy-3-methyl-2-methylene-butyl)-10-(4-methoxy-benzyloxymethyl)-9,14-dioxa-1,5-dithia-dispiro[5.1.5.3]hexadecan-12-ol

上游原料

1-[(4S,6R)-6-(4-Methoxy-benzyloxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-3-[2-((R)-5-methyl-4-methylene-2,6-bis-triethylsilanyloxy-hexyl)-[1,3]dithian-2-yl]-propan-2-one

下游产品

(2R,4S,6R,8R,10S)-10-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-4-(tert-butyl-dimethyl-silanyloxy)-3-methyl-2-methylene-butyl]-8-(4-methoxy-benzyloxymethyl)-1,7-dioxa-spiro[5.5]undecan-4-ol tert-butyl(((2R,4S,6R,8S,10S)-8-((E)-2-((dicyclohexylboraneyl)oxy)but-2-en-1-yl)-10-methoxy-2-(((4-methoxybenzyl)oxy)methyl)-1,7-dioxaspiro[5.5]undecan-4-yl)oxy)dimethylsilane [4-acetoxy-8-(2-{2-acetoxy-5-[10-(tert-butyl-dimethyl-silanyloxy)-8-formyl-4-methoxy-1,7-dioxa-spiro[5.5]undec-2-yl]-1,3-dimethyl-4-oxo-pentyl}-allyl)-10-methyl-10-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-2-yl]-acetic acid allyl ester (2R,6S,8R,10S)-10-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-4-(tert-butyl-dimethyl-silanyloxy)-3-methyl-2-methylene-butyl]-8-(4-methoxy-benzyloxymethyl)-1,7-dioxa-spiro[5.5]undecan-4-one (R)-3-[(2R,4S,6R,8R,10S)-10-(tert-Butyl-dimethyl-silanyloxy)-4-methoxy-8-(4-methoxy-benzyloxymethyl)-1,7-dioxa-spiro[5.5]undec-2-ylmethyl]-2-methyl-but-3-en-1-ol (2R,4S,6R,8R,10S)-4-(tert-Butyl-dimethyl-silanyloxy)-8-[(R)-4-(tert-butyl-dimethyl-silanyloxy)-3-methyl-2-methylene-butyl]-10-methoxy-2-(4-methoxy-benzyloxymethyl)-1,7-dioxa-spiro[5.5]undecane