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(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

CAS号：870528-57-7

英文名：(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

分子式：C29H40N2O7Si

分子量：556.723

合成路线

[(S)-1-(4-Methoxy-phenyl)-ethyl]-[1-(2-trimethylsilanyl-furan-3-yl)-meth-(E)-ylidene]-amine

[(S)-1-(4-Methoxy-phenyl)-ethyl]-[1-(2-trimethylsilanyl-furan-3-yl)-meth-(E)-ylidene]-amine

(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-4-carboxylic acid benzyl ester

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-4-carboxylic acid benzyl ester

(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-3,4-dicarboxylic acid 4-benzyl ester 3-tert-butyl ester

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-3,4-dicarboxylic acid 4-benzyl ester 3-tert-butyl ester

(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

(3S,4S,8S)-8-Isopropyl-2-[(S)-1-(4-methoxy-phenyl)-ethyl]-1,6-dioxo-3-(2-trimethylsilanyl-furan-3-yl)-7-oxa-2,5-diaza-spiro[3.4]octane-5-carboxylic acid tert-butyl ester

上游原料

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-3,4-dicarboxylic acid 4-benzyl ester 3-tert-butyl ester (4S,5S) 5-isopropyl-2-oxo-oxazolidine-4-carboxylic acid benzyl ester [(S)-1-(4-Methoxy-phenyl)-ethyl]-[1-(2-trimethylsilanyl-furan-3-yl)-meth-(E)-ylidene]-amine

下游产品

[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-oxo-2,5-dihydro-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester (1S,4R,5S)-4-(2-Chloro-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione