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(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

CAS号：870528-61-3

英文名：(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

分子式：C20H28N2O5

分子量：376.447

合成路线

[(S)-1-(4-Methoxy-phenyl)-ethyl]-[1-(2-trimethylsilanyl-furan-3-yl)-meth-(E)-ylidene]-amine

[(S)-1-(4-Methoxy-phenyl)-ethyl]-[1-(2-trimethylsilanyl-furan-3-yl)-meth-(E)-ylidene]-amine

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-4-carboxylic acid benzyl ester

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-4-carboxylic acid benzyl ester

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-oxo-2,5-dihydro-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-oxo-2,5-dihydro-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-3,4-dicarboxylic acid 4-benzyl ester 3-tert-butyl ester

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-3,4-dicarboxylic acid 4-benzyl ester 3-tert-butyl ester

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-trimethylsilanyl-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

[(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-trimethylsilanyl-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

(1S,4R,5S)-4-(2-Hydroxy-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-6-[(S)-1-(4-methoxy-phenyl)-ethyl]-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione

上游原料

(4S,5S) 5-isopropyl-2-oxo-oxazolidine-3,4-dicarboxylic acid 4-benzyl ester 3-tert-butyl ester (4S,5S) 5-isopropyl-2-oxo-oxazolidine-4-carboxylic acid benzyl ester [(S)-1-(4-Methoxy-phenyl)-ethyl]-[1-(2-trimethylsilanyl-furan-3-yl)-meth-(E)-ylidene]-amine [(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-oxo-2,5-dihydro-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester [(3S,4S)-3-((S)-1-Hydroxy-2-methyl-propyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-2-oxo-4-(2-trimethylsilanyl-furan-3-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester

下游产品

(1S,4R,5S)-4-(2-Chloro-ethyl)-1-((S)-1-hydroxy-2-methyl-propyl)-2,6-diaza-bicyclo[3.2.0]heptane-3,7-dione