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(2S,9R)-2-(tert-butoxycarbonylamino)-9-(tert-butyldimethylsilyloxy)-8-oxo-6-decanoic acid

(2S,9R)-2-(tert-butoxycarbonylamino)-9-(tert-butyldimethylsilyloxy)-8-oxo-6-decanoic acid

CAS号：874384-12-0

英文名：(2S,9R)-2-(tert-butoxycarbonylamino)-9-(tert-butyldimethylsilyloxy)-8-oxo-6-decanoic acid

分子式：C21H41NO6Si

分子量：431.639

合成路线

(R)-dimethyl (3-((tert-butyldimethylsilyl)oxy)-2-oxobutyl)phosphonate

(R)-dimethyl (3-((tert-butyldimethylsilyl)oxy)-2-oxobutyl)phosphonate

(2S,9R)-2-(tert-butoxycarbonylamino)-9-(tert-butyldimethylsilyloxy)-8-oxo-6-decanoic acid

(2S,9R)-2-(tert-butoxycarbonylamino)-9-(tert-butyldimethylsilyloxy)-8-oxo-6-decanoic acid

(S)-2-dibenzylamino-5-hydroxypentanoic acid benzyl ester

(S)-2-dibenzylamino-5-hydroxypentanoic acid benzyl ester

(2S,9R)-2-(tert-butoxycarbonylamino)-9-(tert-butyldimethylsilyloxy)-8-oxo-6-decanoic acid

(2S,9R)-2-(tert-butoxycarbonylamino)-9-(tert-butyldimethylsilyloxy)-8-oxo-6-decanoic acid

上游原料

(R)-dimethyl (3-((tert-butyldimethylsilyl)oxy)-2-oxobutyl)phosphonate (S)-2-dibenzylamino-5-hydroxypentanoic acid benzyl ester

下游产品

(R)-1-{(S)-2-[2-((2S,9R)-2-Amino-9-hydroxy-8-oxo-decanoylamino)-2-methyl-propionylamino]-3-phenyl-propionyl}-pyrrolidine-2-carboxylic acid (-)-(3S,9S,14aR)-9-benzyl-3-[(R)-7-hydroxy-6-oxooctyl]-6,6-dimethyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone