百科

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

CAS号：874384-21-1

英文名：(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

分子式：C39H64N4O9Si

分子量：761.032

合成路线

874384-02-8

(S)-2-(dibenzylamino)-6-oxohexanoic acid benzyl ester

874384-21-1

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

874384-04-0

(R)-dimethyl (3-((tert-butyldimethylsilyl)oxy)-2-oxobutyl)phosphonate

874384-21-1

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

850209-98-2

(S)-2-dibenzylamino-5-hydroxypentanoic acid benzyl ester

874384-21-1

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

874384-01-7

benzyl (S)-2-(dibenzylamino)pent-4-enoate

874384-21-1

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

874384-03-9

(E)-(S)-2-Dibenzylamino-6-methoxy-hex-5-enoic acid benzyl ester

874384-21-1

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

167905-35-3

Bzl-N(Bzl)Glu(OBzl)-OBzl

874384-21-1

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

850209-99-3

2-dibenzylamino-5-oxo-pentanoic acid benzyl ester

874384-21-1

(R)-1-((S)-2-{2-[(2S,9R)-2-tert-Butoxycarbonylamino-9-(tert-butyl-dimethyl-silanyloxy)-8-oxo-decanoylamino]-2-methyl-propionylamino}-3-phenyl-propionyl)-pyrrolidine-2-carboxylic acid

上游原料

(R)-dimethyl (3-((tert-butyldimethylsilyl)oxy)-2-oxobutyl)phosphonate Bzl-N(Bzl)Glu(OBzl)-OBzl benzyl (S)-2-(dibenzylamino)pent-4-enoate 2-dibenzylamino-5-oxo-pentanoic acid benzyl ester (S)-2-dibenzylamino-5-hydroxypentanoic acid benzyl ester (E)-(S)-2-Dibenzylamino-6-methoxy-hex-5-enoic acid benzyl ester (S)-2-(dibenzylamino)-6-oxohexanoic acid benzyl ester

下游产品

(R)-1-{(S)-2-[2-((2S,9R)-2-Amino-9-hydroxy-8-oxo-decanoylamino)-2-methyl-propionylamino]-3-phenyl-propionyl}-pyrrolidine-2-carboxylic acid (-)-(3S,9S,14aR)-9-benzyl-3-[(R)-7-hydroxy-6-oxooctyl]-6,6-dimethyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone