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Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

CAS号：880144-45-6

英文名：Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

分子式：C29H36F2N2O8

分子量：578.602

合成路线

Benzyl (2R,5E)-2-(bis{[(2-methyl-2-propanyl)oxy]carbonyl}amino)-6 -nitro-5-hexenoate

Benzyl (2R,5E)-2-(bis{[(2-methyl-2-propanyl)oxy]carbonyl}amino)-6 -nitro-5-hexenoate

2,3-二氟苯硼酸

2,3-二氟苯硼酸

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

二碳酸二叔丁酯

二碳酸二叔丁酯

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate

1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-norval inate

Benzyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-norval inate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

D-叔丁氧羰基-L-谷氨酸α苄脂

D-叔丁氧羰基-L-谷氨酸α苄脂

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate

上游原料

1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate 二碳酸二叔丁酯 D-叔丁氧羰基-L-谷氨酸α苄脂 2,3-二氟苯硼酸 Benzyl (2R,5E)-2-(bis{[(2-methyl-2-propanyl)oxy]carbonyl}amino)-6 -nitro-5-hexenoate Benzyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-norval inate

下游产品

(3R,6s)-3-氨基-6-(2,3-二氟苯基)-1-(2,2,2-三氟乙基)氮杂环庚烷-2-酮 2-Methyl-2-propanyl [(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-3-azepa nyl]carbamate (5S)-5-(2,3-Difluorophenyl)-N<sup>2</sup>,N<sup>2</sup>-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine