百科

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

CAS号：880145-43-7

英文名：diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

分子式：C17H29O5PSi

分子量：372.468

合成路线

(3aS,7S,7aR)-4-bromo-7-(trimethylsilyl)-3a,6,7,7a-tetrahydro-1-benzofuran-2(3H)-one

(3aS,7S,7aR)-4-bromo-7-(trimethylsilyl)-3a,6,7,7a-tetrahydro-1-benzofuran-2(3H)-one

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

(3S)-3-[(2R)-5-oxo-2,5-dihydrofuran-2-yl]-3-(trimethylsilyl)propanal

(3S)-3-[(2R)-5-oxo-2,5-dihydrofuran-2-yl]-3-(trimethylsilyl)propanal

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

(5R)-5-[(1S)-4,4-dibromo-1-(trimethylsilyl)but-3-en-1-yl]furan-2(5H)-one

(5R)-5-[(1S)-4,4-dibromo-1-(trimethylsilyl)but-3-en-1-yl]furan-2(5H)-one

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

3-trimethylsilylprop-2-enal

3-trimethylsilylprop-2-enal

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

diethyl [(3S,3aR,7S,7aR)-2-oxo-7-(trimethylsilyl)-4-vinyl-2,3,3a,6,7,7a-hexahydro-1-benzofuran-3-yl]phosphonate

上游原料

(3aS,7S,7aR)-4-bromo-7-(trimethylsilyl)-3a,6,7,7a-tetrahydro-1-benzofuran-2(3H)-one (3S)-3-[(2R)-5-oxo-2,5-dihydrofuran-2-yl]-3-(trimethylsilyl)propanal 3-trimethylsilylprop-2-enal (5R)-5-[(1S)-4,4-dibromo-1-(trimethylsilyl)but-3-en-1-yl]furan-2(5H)-one

下游产品

(3S,3aR,7S,7aR)-3-[(1S)-1-methylprop-2-en-1-yl]-7-(trimethylsilyl)-4-vinyl-3a,6,7,7a-tetrahydro-1-benzofuran-2(3H)-one (1R,2S,7S,8S,8aR)-8-(hydroxymethyl)-7-methyl-2-(trimethylsilyl)-1,2,3,7,8,8a-hexahydronaphthalen-1-ol (1R,2R,6S)-2-[(1S,2S)-1-(hydroxymethyl)-2-methylbut-3-en-1-yl]-6-(trimethylsilyl)-3-vinylcyclohex-3-en-1-ol