百科

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

CAS号：881423-95-6

英文名：Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

分子式：C36H39BrN2O7Si

分子量：719.694

合成路线

[(3aR,4R,6aR)-6-Allyl-6-(4-bromo-phenyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-tert-butyl-diphenyl-silane

[(3aR,4R,6aR)-6-Allyl-6-(4-bromo-phenyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-tert-butyl-diphenyl-silane

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

(3aS,5R,6R,6aR)-3a-(4-Bromo-phenyl)-5-(tert-butyl-diphenyl-silanyloxymethyl)-hexahydro-furo[3,2-b]furan-2,6-diol

(3aS,5R,6R,6aR)-3a-(4-Bromo-phenyl)-5-(tert-butyl-diphenyl-silanyloxymethyl)-hexahydro-furo[3,2-b]furan-2,6-diol

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

1-(4-bromophenyl)-5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose

1-(4-bromophenyl)-5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

Acetic acid (2R,3R,3aR,5S,6aS)-6a-(4-bromo-phenyl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-yl ester

上游原料

1-(4-bromophenyl)-5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-D-ribofuranose (3aS,5R,6R,6aR)-3a-(4-Bromo-phenyl)-5-(tert-butyl-diphenyl-silanyloxymethyl)-hexahydro-furo[3,2-b]furan-2,6-diol [(3aR,4R,6aR)-6-Allyl-6-(4-bromo-phenyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethoxy]-tert-butyl-diphenyl-silane

下游产品

1-[(1R,3S,5S,7R,8R)-5-(4-bromophenyl)-8-hydroxy-7-(hydroxymethyl)-2,6-dioxabicyclo[3.3.0]octan-3-yl]thymine