化合物简介
Methyl 7-Methoxy-2H-indazole-3-carboxylate is an intermediate in the synthesis of 7-Hydroxy Granisetron, a metabolite of Granisetron, a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.
基本信息
中文名称
7-甲氧基-1H-吲唑-3-羧酸甲酯
英文名称
methyl 7-methoxy-2H-indazole-3-carboxylate
中文别名
英文别名
1H-Indazole-3-carboxylicacid,7-methoxy-,methyl ester、METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
CAS号
885278-95-5
分子式
C10H10N2O3
分子量
206.198
精确质量
206.069
PSA
64.21
LOGP
1.3581
安全信息
海关编码
2933990090
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