1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil

1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil

CAS号：887486-79-5

英文名：1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil

分子式：C24H44N2O8Si2

分子量：544.786

合成路线

1-[(2R,3R,3aR,7aR)-3-(tert-Butyl-dimethyl-silanyloxy)-3a-hydroxy-5-oxo-hexahydro-furo[2,3-c]pyran-2-yl]-1H-pyrimidine-2,4-dione

1-[(2R,3R,3aR,7aR)-3-(tert-Butyl-dimethyl-silanyloxy)-3a-hydroxy-5-oxo-hexahydro-furo[2,3-c]pyran-2-yl]-1H-pyrimidine-2,4-dione

1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil

1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil

Bromo-acetic acid (2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-oxo-tetrahydro-furan-2-ylmethyl ester

Bromo-acetic acid (2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-oxo-tetrahydro-furan-2-ylmethyl ester

1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil

1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil

上游原料

Bromo-acetic acid (2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-oxo-tetrahydro-furan-2-ylmethyl ester 1-[(2R,3R,3aR,7aR)-3-(tert-Butyl-dimethyl-silanyloxy)-3a-hydroxy-5-oxo-hexahydro-furo[2,3-c]pyran-2-yl]-1H-pyrimidine-2,4-dione

下游产品

1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(trans-ethoxycarbonylethenyl)-β-D-ribo-pentofuranosyl]uracil 1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(ethoxycarbonylethenyl)-β-D-ribo-pentofuranosyl]cytosine 1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonyl)-β-D-ribo-pentofuranosyl]uracil 1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(ethoxycarbonylethyl)-β-D-ribo-pentofuranosyl]cytosine (2R,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-3-carbaldehyde 1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(2-phenylselenylethyl)-β-D-ribo-pentofuranosyl]uracil 1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonyl)-β-D-ribo-pentofuranosyl]cytosine 1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(2-mesyloxyethyl)-β-D-ribo-pentofuranosyl]uracil 1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-ethenyl-β-D-ribo-pentofuranosyl]uracil