百科

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

CAS号：889454-40-4

英文名：(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

分子式：C42H73BrO8Si2

分子量：842.099

合成路线

(R)-3-(3,4-Dimethoxy-benzyloxy)-N-methoxy-2,N-dimethyl-propionamide

(R)-3-(3,4-Dimethoxy-benzyloxy)-N-methoxy-2,N-dimethyl-propionamide

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

(2R,3S,5S,6E,9R,10E,12E)-9-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-5-methoxy-13-bromo-2,7-dimethyl-3-triethylsilyloxy-trideca-6,10,12-triene

(2R,3S,5S,6E,9R,10E,12E)-9-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-5-methoxy-13-bromo-2,7-dimethyl-3-triethylsilyloxy-trideca-6,10,12-triene

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

(2R,5S,6E,9R,10E,12E)-9-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-5-hydroxy-13-bromo-2,7-dimethyl-trideca-6,10,12-trien-3-one

(2R,5S,6E,9R,10E,12E)-9-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-5-hydroxy-13-bromo-2,7-dimethyl-trideca-6,10,12-trien-3-one

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

(2R,5S,6R,7S,9S,10E,13R,14E,16E)-13-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-17-bromo-5-hydroxy-9-methoxy-7-triethylsilyloxy-2,6,11-trimethyl-heptadeca-10,14,16-trien-3-one

上游原料

(2R,5S,6E,9R,10E,12E)-9-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-5-hydroxy-13-bromo-2,7-dimethyl-trideca-6,10,12-trien-3-one (R)-3-(3,4-Dimethoxy-benzyloxy)-N-methoxy-2,N-dimethyl-propionamide (2R,3S,5S,6E,9R,10E,12E)-9-(tert-butyldimethylsilyloxy)-1-(3,4-dimethoxybenzyloxy)-5-methoxy-13-bromo-2,7-dimethyl-3-triethylsilyloxy-trideca-6,10,12-triene

下游产品

(E)-(1S,2S,5R,9S,11S,12R,13S)-5-((1E,3E)-4-Bromo-buta-1,3-dienyl)-1,13-dihydroxy-9-methoxy-2,7,12-trimethyl-4,15-dioxa-bicyclo[9.3.1]pentadec-7-en-3-one (S)-2-[(2S,4S,5S,6S)-6-[(3E,7E,9E)-(2S,6R)-10-Bromo-6-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-4-methyl-deca-3,7,9-trienyl]-4-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-5-methyl-tetrahydro-pyran-2-yl]-propionic acid