百科

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

CAS号：912641-68-0

英文名：(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

分子式：C23H40O6

分子量：412.56

合成路线

(2R,3R,4S,5R)-1-hydroxy-2,3:4,5-di-O-isopropylidene-1-O-trityl-2,3,4,5-tetraoxooctane

(2R,3R,4S,5R)-1-hydroxy-2,3:4,5-di-O-isopropylidene-1-O-trityl-2,3,4,5-tetraoxooctane

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

(2R,3R,4S,5R)-2,3:4,5-di-O-isopropylidene-1-O-trityl-1,2,3,4,5-pentaoxo-7-octene

(2R,3R,4S,5R)-2,3:4,5-di-O-isopropylidene-1-O-trityl-1,2,3,4,5-pentaoxo-7-octene

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

5-iodopentanoic acid

5-iodopentanoic acid

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

(5Z,7R,8R,9S,10R)-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridec-5-enoic acid tert-butyl ester

上游原料

5-iodopentanoic acid (2R,3R,4S,5R)-2,3:4,5-di-O-isopropylidene-1-O-trityl-1,2,3,4,5-pentaoxo-7-octene (2R,3R,4S,5R)-1-hydroxy-2,3:4,5-di-O-isopropylidene-1-O-trityl-2,3,4,5-tetraoxooctane

下游产品

(5R,6R,7R,8R,9S,10R)-5,6-dihydroxy-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridecanoic acid tert-butyl ester (5S,6S,7R,8R,9S,10R)-5,6-dihydroxy-7,8:9,10-di-O-isopropylidene-7,8,9,10-tetraoxotridecanoic acid tert-butyl ester