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methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

CAS号：935248-73-0

英文名：methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

分子式：C26H46O8Si

分子量：514.724

合成路线

E-7-(tert-butyl-dimethyl-silanyloxy)-3-[2-hydroxy-3-(2,2,5-trimethyl-[1,3]dioxolan-4-yl)-propyl]-6,6-dimethyl-hept-2-en-4-ynoic acid methyl ester

E-7-(tert-butyl-dimethyl-silanyloxy)-3-[2-hydroxy-3-(2,2,5-trimethyl-[1,3]dioxolan-4-yl)-propyl]-6,6-dimethyl-hept-2-en-4-ynoic acid methyl ester

methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

tert-butyl((2,2-dimethylbut-3-yn-1-yl)oxy)dimethylsilane

tert-butyl((2,2-dimethylbut-3-yn-1-yl)oxy)dimethylsilane

methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

(S)-5-hydroxy-6-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hex-2-ynoic acid methyl ester

(S)-5-hydroxy-6-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hex-2-ynoic acid methyl ester

methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

methyl (E)-2-((2S,6S)-2-(1-((tert-butyldimethylsilyl)oxy)-2-methylpropan-2-yl)-2-methoxy-3-oxo-6-(((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)methyl)tetrahydro-4H-pyran-4-ylidene)acetate

上游原料

(S)-5-hydroxy-6-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hex-2-ynoic acid methyl ester E-7-(tert-butyl-dimethyl-silanyloxy)-3-[2-hydroxy-3-(2,2,5-trimethyl-[1,3]dioxolan-4-yl)-propyl]-6,6-dimethyl-hept-2-en-4-ynoic acid methyl ester tert-butyl((2,2-dimethylbut-3-yn-1-yl)oxy)dimethylsilane

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