百科

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

CAS号：942618-58-8

英文名：(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

分子式：C30H43NO9SSi

分子量：621.814

合成路线

942618-30-6

(4S)-4-benzyloxycarbonylamino-6',7'-epoxy-1',3,4,4',4'a,8'a-hexahydrospiro[furan-2(5H),5'(8'H)-1',4'-methanonaphthalene]-5',8'-dione

942618-58-8

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

942618-57-7

benzyl ((1'S,2S,4S,4'R,4a'S,6'S,8a'R)-6'-hydroxy-5,8'-dioxo-4,4',4a',5,6',7',8',8a'-octahydro-1'H,3H-spiro[furan-2,5'-[1,4]methanonaphthalen]-4-yl)carbamate

942618-58-8

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

942618-31-7

(1S,4R,4'S,4aS,5S,6S,8aR)-4'-benzyloxycarbonylamino-6-triethylsilyloxy-1,3',4',4,4a,6,7,8a-octahydrospiro[furan-2'(5H),5(8H)-1,4-methanonaphthalene]-5',8-dione

942618-58-8

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

942618-35-1

(3S,5S,6R,7S,8R,10S)-3-benzyloxycarbonylamino-8-(4-methylbenzenesulfonyl)-6,7-epoxy-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-en-2-one

942618-58-8

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

942618-32-8

(3S,5S,10S)-3-benzyloxycarbonylamino-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-ene-2,8-dione

942618-58-8

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

942618-33-9

(3S,5S,8R,10S)-3-benzyloxycarbonylamino-8-hydroxy-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-en-2-one

942618-58-8

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

942618-34-0

(3S,5S,6R,7R,8R,10S)-3-benzyloxycarbonylamino-6,7-epoxy-8-hydroxy-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-en-2-one

942618-58-8

(1S,2R,4S,5S,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-5-hydroxy-4-((triethylsilyl)oxy)-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate

上游原料

benzyl ((1'S,2S,4S,4'R,4a'S,6'S,8a'R)-6'-hydroxy-5,8'-dioxo-4,4',4a',5,6',7',8',8a'-octahydro-1'H,3H-spiro[furan-2,5'-[1,4]methanonaphthalen]-4-yl)carbamate (3S,5S,8R,10S)-3-benzyloxycarbonylamino-8-hydroxy-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-en-2-one (3S,5S,10S)-3-benzyloxycarbonylamino-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-ene-2,8-dione (1S,4R,4'S,4aS,5S,6S,8aR)-4'-benzyloxycarbonylamino-6-triethylsilyloxy-1,3',4',4,4a,6,7,8a-octahydrospiro[furan-2'(5H),5(8H)-1,4-methanonaphthalene]-5',8-dione (4S)-4-benzyloxycarbonylamino-6',7'-epoxy-1',3,4,4',4'a,8'a-hexahydrospiro[furan-2(5H),5'(8'H)-1',4'-methanonaphthalene]-5',8'-dione (3S,5S,6R,7S,8R,10S)-3-benzyloxycarbonylamino-8-(4-methylbenzenesulfonyl)-6,7-epoxy-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-en-2-one (3S,5S,6R,7R,8R,10S)-3-benzyloxycarbonylamino-6,7-epoxy-8-hydroxy-10-triethylsilyloxy-1-oxaspiro[4,5]dec-6-en-2-one

下游产品

(1S,2R,4S,5R,6R)-5-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropyl)-4,5-dihydroxy-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate (2'S,2''E,4R,4''E,5R,6S,6''E,8''R,10''S,12''E,14''R)-4,5-epoxy-6-hydroxy-6-[2'-(8'',10'',12'',14''-tetramethylhexadeca-2'',4'',6'',12''-tetraenoylamino)-3'-tert-butyldiphenylsilyloxypropyl]-2-cyclohexen-1-one (1R,2R,2'S,2''E,3S,4R,4''E,6S,6''S,6''E,8''R,10''S,12''E,14''R)-1-[3'-tert-butyldiphenylsilyloxy-2'-(8'',10'',12'',14''-tetramethylhexadeca-2'',4'',6'',12''-tetraenoylamino)propyl]-2,3-epoxy-6-hydroxy-4-(4-methylbenzenesulfonyl)cyclohexan-1-ol (1R,2R,2'S,3S,4R,6S)-1-(2'-benzyloxycarbonylamino-3'-tert-bityldiphenylsilyloxypropyl)-2,3-epoxy-6-hydroxy-4-(4-methylbenzenesulfonyl)cyclohexan-1-ol (1S,2R,4S,5R,6R)-5-((S)-2-amino-3-((tert-butyldiphenylsilyl)oxy)propyl)-4,5-dihydroxy-7-oxabicyclo[4.1.0]heptan-2-yl 4-methylbenzenesulfonate