百科

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

CAS号：943779-58-6

英文名：tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

分子式：C37H40N6O4S

分子量：664.816

合成路线

4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

methyl 4-chloro-3-nitrobenzoate

methyl 4-chloro-3-nitrobenzoate

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

methyl 4-chloro-3-nitrobenzoate

methyl 4-chloro-3-nitrobenzoate

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

3-amino-4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-benzoic acid methyl ester

3-amino-4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-benzoic acid methyl ester

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (S)-(4-((4-((3-hydroxy-1-phenylpropyl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

上游原料

methyl 4-chloro-3-nitrobenzoate 3-amino-4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-benzoic acid methyl ester 4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester methyl 4-chloro-3-nitrobenzoate

下游产品

(S)-4-((4-aminophenyl)thio)-N-(3-hydroxy-1-phenylpropyl)-3-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)benzamide