百科

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

CAS号：943780-65-2

英文名：tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

分子式：C37H38N6O3S

分子量：646.801

合成路线

4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

methyl 4-chloro-3-nitrobenzoate

methyl 4-chloro-3-nitrobenzoate

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

methyl 4-chloro-3-nitrobenzoate

methyl 4-chloro-3-nitrobenzoate

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

3-amino-4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-benzoic acid methyl ester

3-amino-4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-benzoic acid methyl ester

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

tert-butyl (R)-(4-((4-((2,3-dihydro-1H-inden-1-yl)carbamoyl)-2-((7-isopropylpyrido[2,3-d]pyrimidin-4-yl)amino)phenyl)thio)phenyl)carbamate

上游原料

methyl 4-chloro-3-nitrobenzoate 3-amino-4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-benzoic acid methyl ester 4-(4-tert-butoxycarbonylamino-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester methyl 4-chloro-3-nitrobenzoate

下游产品