百科

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

CAS号：952057-16-8

英文名：(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

分子式：C11H17NO4

分子量：227.257

合成路线

(-)-(3R,4S,5R)-5-hydroxy-3,4-(isopropylidenedioxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(-)-(3R,4S,5R)-5-hydroxy-3,4-(isopropylidenedioxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[4-oxo-4-(trimethylsilyl)butyl]pyrrolidin-2-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[4-oxo-4-(trimethylsilyl)butyl]pyrrolidin-2-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(-)-(3R,4S,5R)-5-hydroxy-3,4-(isopropylidenedioxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(-)-(3R,4S,5R)-5-hydroxy-3,4-(isopropylidenedioxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8S,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8S,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8S,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8S,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[4-oxo-4-(trimethylsilyl)butyl]pyrrolidin-2-one

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[4-oxo-4-(trimethylsilyl)butyl]pyrrolidin-2-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8R,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8S,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

(1R,2R,8S,8aR)-8-hydroxy-1,2-(isopropylidenedioxy)-1,5,6,7,8,8a-hexahydro-2H-indolizin-3-one

上游原料

(-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[4-oxo-4-(trimethylsilyl)butyl]pyrrolidin-2-one (-)-(3R,4S,5R)-5-hydroxy-3,4-(isopropylidenedioxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one (-)-(3R,4S,5R)-3,4-(isopropylidenedioxy)-5-(phenoxythiocarbonyloxy)-1-[3-(2-trimethylsilyl-1,3-dithian-2-yl)propyl]pyrrolidin-2-one

下游产品

(1R,2S,8R,8aR)-octahydro-1,2,8-indolizinetriol