百科

(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one

(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one

CAS号：97211-42-2

英文名：(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one

分子式：C25H39FO6

分子量：454.572

合成路线

(+)-3,3aα,4α,5β,6α,6aα-hexahydro-5-hydroxy-6-iodo-4-<1-fluoro-3(S*)-hydroxy-1(Z)-octen-1-yl>-2H-cyclopenta<b>-furan-2-one

(+)-3,3aα,4α,5β,6α,6aα-hexahydro-5-hydroxy-6-iodo-4-<1-fluoro-3(S*)-hydroxy-1(Z)-octen-1-yl>-2H-cyclopenta<b>-furan-2-one

(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one

(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one

[(1S,4R,5R)-5-((Z)-(S)-1-Fluoro-3-hydroxy-oct-1-enyl)-4-hydroxy-cyclopent-2-enyl]-acetic acid

[(1S,4R,5R)-5-((Z)-(S)-1-Fluoro-3-hydroxy-oct-1-enyl)-4-hydroxy-cyclopent-2-enyl]-acetic acid

(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one

(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one

上游原料

(+)-3,3aα,4α,5β,6α,6aα-hexahydro-5-hydroxy-6-iodo-4-<1-fluoro-3(S*)-hydroxy-1(Z)-octen-1-yl>-2H-cyclopenta<b>-furan-2-one [(1S,4R,5R)-5-((Z)-(S)-1-Fluoro-3-hydroxy-oct-1-enyl)-4-hydroxy-cyclopent-2-enyl]-acetic acid

下游产品

(3aR,4R,5R,6aS)-4-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-ol (+)-13-fluoroprostaglandin F2α methyl ester (Z)-7-[(1R,2R,3R,5S)-2-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid (Z)-7-[(1R,2R,3R,5S)-2-[(Z)-(S)-1-Fluoro-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid methyl ester