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2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

CAS号：98362-08-4

英文名：2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

分子式：C11H16F3NO5

分子量：299.244

合成路线

Methanesulfonic acid (R)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-{(4R,5R)-2,2-dimethyl-5-[(2,2,2-trifluoro-acetylamino)-methyl]-[1,3]dioxolan-4-yl}-methyl ester

Methanesulfonic acid (R)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-{(4R,5R)-2,2-dimethyl-5-[(2,2,2-trifluoro-acetylamino)-methyl]-[1,3]dioxolan-4-yl}-methyl ester

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

Methanesulfonic acid (1R,2R)-1-{(4R,5R)-2,2-dimethyl-5-[(2,2,2-trifluoro-acetylamino)-methyl]-[1,3]dioxolan-4-yl}-2,3-dihydroxy-propyl ester

Methanesulfonic acid (1R,2R)-1-{(4R,5R)-2,2-dimethyl-5-[(2,2,2-trifluoro-acetylamino)-methyl]-[1,3]dioxolan-4-yl}-2,3-dihydroxy-propyl ester

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

(R)-((4S,5R)-5-Aminomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol

(R)-((4S,5R)-5-Aminomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

N-{(4R,5S)-5-[(R)-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl}-2,2,2-trifluoro-acetamide

N-{(4R,5S)-5-[(R)-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl}-2,2,2-trifluoro-acetamide

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

2,2,2-Trifluoro-N-[(4R,5R)-5-((2S,3R)-3-hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide

上游原料

N-{(4R,5S)-5-[(R)-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl}-2,2,2-trifluoro-acetamide (R)-((4S,5R)-5-Aminomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol Methanesulfonic acid (R)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-{(4R,5R)-2,2-dimethyl-5-[(2,2,2-trifluoro-acetylamino)-methyl]-[1,3]dioxolan-4-yl}-methyl ester Methanesulfonic acid (1R,2R)-1-{(4R,5R)-2,2-dimethyl-5-[(2,2,2-trifluoro-acetylamino)-methyl]-[1,3]dioxolan-4-yl}-2,3-dihydroxy-propyl ester

下游产品

(3aR,8aS,9S,9aS)-2,2-Dimethyl-octahydro-[1,3]dioxolo[4,5-f]indolizin-9-ol 2,2,2-Trifluoro-N-[(4R,5R)-5-((2R,3S)-3-formyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-acetamide