普拉格雷

普拉格雷

CAS号:150322-43-3
英文名:Prasugrel
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化合物简介
Prasugrel (trade name Effient in the US and India, and Efient in the EU) is a pharmaceutical drug that acts as a platelet inhibitor and is used to prevent thrombosis (blood clotting). It was developed by Daiichi Sankyo Co. and produced by Ube and currently marketed in the United States in cooperation with Eli Lilly and Company.
基本信息
编号系统
物化性质
生产方法及用途
用途
适应症:普拉格雷新型血栓预防药物Effient(prasugrel,普拉格雷)用于预防接受经皮冠状动脉介入(PCI)治疗后的冠脉综合症患者的血栓形成。Effient帮助预防血小板凝聚成块,在接受PCI手术后使用阿司匹林与Effient已证明可降低冠脉综合症患者发生心血管事件的风险。
上游原料
5-benzyl-2-methoxy-4,5,6,7-tetrahydrothieno[3,2-c]pyridine 4,5,6,7-四氢噻吩并[3,2-c]吡啶-2-醇 2-乙酸酯盐酸盐 5-benzyl-2-bromo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid 3-cyclopropyl-1-(2-fluorophenyl)-3-oxopropyl methanesulfonate prasugrel maleate salt 2-(2-fluorophenyl)-N-methoxy-N-methylacetamide 5,6,7,7a-四氢噻吩并[3,2-c]吡啶-2(4H)-酮盐酸盐 4,5,6,7-四氢噻吩并[3,2-c]吡啶盐酸盐 4,5,6,7-四氢噻吩并[3.2-c]吡啶 脱乙酰基2-O-叔-丁基二甲基硅烷基普拉格雷 2-methoxy-4,5,6,7-tetrahydrothieno[3,2-c]pyridine 4-methylbenzenesulfonic acid compound with (4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid (1:1) 乙酸异丙烯酯 5,6,7,7a-四氢-5-(三苯甲基)噻吩并[3,2-c]吡啶酮 5,6,7,7a-四氢噻吩并[3,2-c]吡啶-2(4H)-酮对甲苯磺酸盐 N-三苯甲基-4,5,6,7-四氢噻吩并[3,2-c]吡啶 2-(N-morpholinyl)-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4.5.6.7-tetrahydro-thieno-[3,2-c]pyridine 2-噻吩乙胺 2-(4-morpholinyl)-N-tert-butyloxycarbonyl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine 2-氟苯乙酸 乙酰氯 2-(4-morpholinyl)-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine 乙酸酐 5-benzyl-6,7-dihydro-4H-thieno[3,2-c]pyridine 1-环丙基-2-(2-氟苯基)乙酮 邻氟氯苄 2-氟溴苄 2-溴-6,7-二氢噻吩并[3,2-C]吡啶--5(4H)-甲酸叔丁酯 2-溴-2-(2-氟苯基)-1-环丙基乙酮 5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-2-oxo-2,4,5,6,7,7a-hexahydro thieno [3,2-c] pyridine hydrobromide 2-bromo-2-(2-fluorophenyl)acetonitrile 5-[2-环丙基-1-(2-氟苯基)-2-氧代乙基]-5,6,7,7a-四氢噻吩并[3,2-c]吡啶-2(4H)-酮 2-(2-fluorophenyl)-2-(2-methoxy-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetonitrile 5-[2-环丙基-1-(2-氟苯基)-2-氧代乙基]-4,5,6,7-四氢噻吩并[3,2-c]吡啶-2(3H)-酮 2-氟苯基乙腈 2-氧代-2,4,5,6,7a-六氢噻吩并[3,2-c]吡啶盐酸盐 5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-2-oxo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrobromide (5-trityl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid 2-acetoxy-4,5,6,7-tetrahydrothieno[3,2-c]pyridine p-toluenesulfonate 4,5,6,7-四氢噻吩并[3,2-c]吡啶-2(3H)-酮 4-甲基苯磺酸盐