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佛司可林

佛司可林

CAS号：66575-29-9

英文名：FORSKOLIN

分子式

C22H34O7

熔点

282-232ºC

密度

1.23 g/cm3

分子量

410.501

沸点

519.9ºC at 760 mmHg

溶解度

信号词

Warning

危险品标志

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化合物简介

Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.

基本信息

中文名称

佛司可林

英文名称

FORSKOLIN

中文别名

毛喉萜、考福新、毛喉素、弗斯可林、佛司可林, 来源于毛喉鞘蕊花

英文别名

7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one、HL 362、ForsLean、COLFORSIN、FORSKOHLIN、[3H]-Forskolin、L 75-1362B、Forskolin, 98%, from Coleus forskohlii

CAS号

66575-29-9

分子式

C22H34O7

分子量

410.501

精确质量

410.23

PSA

113.29

LOGP

1.5199

编号系统

MDL号

MFCD00082317

物化性质

外观与性状

无色结晶固体

密度

1.23 g/cm3

沸点

519.9ºC at 760 mmHg

熔点

282-232ºC

闪点

171.8ºC

折射率

1.551

储存条件

库房通风低温干燥,与强酸,强碱,食品分开储运

安全信息

RTECS号

QL6150000

安全说明

S22; S36/37

危险类别码

R21

危险品标志

Xn

危险性描述

H312

危险性防范说明

P280

信号词

Warning

危险标志

GHS07

生产方法及用途

生产方法

从植物中提取的腺苷酸环化酶直接激活剂。

合成路线

共找到1条合成路线 >

乙酸酐

1alpha,6beta,7beta,9alpha-四羟基-8,13-环氧-赖百当-14-烯-11-酮

1alpha,6beta,7beta,9alpha-四羟基-8,13-环氧-赖百当-14-烯-11-酮

佛司可林

上游原料

共找到13个上游原料 >

(6S,11S,16S,1R,2R,12R,13R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.0.2,607,12]heptadec-14-en-11,13-diol

(6S,11S,16S,1R,2R,12R,13R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.0.2,607,12]heptadec-14-en-11,13-diol

(1S,6S,11S,12S,2R,16R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.02,607,12]heptadec-13-en-11-ol

(1S,6S,11S,12S,2R,16R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.02,607,12]heptadec-13-en-11-ol

乙酸酐

(13R)-Spiroforskolin

(13R)-Spiroforskolin

(1S,6S,12S,16S,2R)-14-hydroxy-4,4,7,9,13,17,17-heptamethyl-3,5,8-trioxa-9-vinyltetracyclo[11.4.0.0.2,607,12]heptadecan-11-one

(1S,6S,12S,16S,2R)-14-hydroxy-4,4,7,9,13,17,17-heptamethyl-3,5,8-trioxa-9-vinyltetracyclo[11.4.0.0.2,607,12]heptadecan-11-one

(1S,7S,9S,3R,5R,8R,14R)-14-acetyloxy-8,9-dihydroxy-1,5,7,11,11-pentamethyl-6-oxa-5-vinyltricyclo[8.4.0.02,7]tetradec-3-yl acetate

(1S,7S,9S,3R,5R,8R,14R)-14-acetyloxy-8,9-dihydroxy-1,5,7,11,11-pentamethyl-6-oxa-5-vinyltricyclo[8.4.0.02,7]tetradec-3-yl acetate

下游产品

共找到1个下游商品 >

毛喉帖 J

上游原料

(6S,11S,16S,1R,2R,12R,13R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.0.2,607,12]heptadec-14-en-11,13-diol (1S,6S,11S,12S,2R,16R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.02,607,12]heptadec-13-en-11-ol 乙酸酐 (13R)-Spiroforskolin (1S,6S,12S,16S,2R)-14-hydroxy-4,4,7,9,13,17,17-heptamethyl-3,5,8-trioxa-9-vinyltetracyclo[11.4.0.0.2,607,12]heptadecan-11-one (1S,7S,9S,3R,5R,8R,14R)-14-acetyloxy-8,9-dihydroxy-1,5,7,11,11-pentamethyl-6-oxa-5-vinyltricyclo[8.4.0.02,7]tetradec-3-yl acetate (1S,6S,12S,2R,11R,14R,16R)-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.02,6.07,12]heptadecane-11,14-diol (1S,6S,12S,16S,2R,11R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.0.2,607,12]heptadec-14-en-11-ol (2S,7S,13S,6R,9R,11R,14R)-14-acetyloxy-4,4,7,9,13,17,17-heptamethyl-3,5,8-trioxa-9-vinyltetracyclo[11.4.0.02,6.07,12]heptadec-11-yl acetate 1alpha,6beta,7beta,9alpha-四羟基-8,13-环氧-赖百当-14-烯-11-酮 (2S,7S,13S,14S,6R,9R)-14-hydroxy-4,4,7,9,13,17,17-heptamethyl-3,5,8-trioxa-9-vinyltetracyclo[11.4.0.02,607,12]heptadec-11-one (2S,7S,13S,6R,9R,14R)-14-hydroxy-4,4,7,9,13,17,17-heptamethyl-3,5,8-trioxa-9-vinyltetracyclo[11.4.0.02,6.07,12]heptadecan-11-one (1S,6S,11S,12S,2R)-14-methoxy-1,4,4,8,8,12,16-heptamethyl-3,5,17-trioxa-16-vinyltetracyclo[11.4.0.0.2,607,12]heptadec-14-en-11-ol

下游产品