CB 300919; 4-[[[7-氯-3,4-二氢-3-甲基-2-[(4-甲基-1-哌嗪基)甲基]-4-氧代-6-喹唑啉基]甲基]-2-丙炔-1-基氨基]-N-(3-吡啶基甲基)苯甲酰胺

CB 300919; 4-[[[7-氯-3,4-二氢-3-甲基-2-[(4-甲基-1-哌嗪基)甲基]-4-氧代-6-喹唑啉基]甲基]-2-丙炔-1-基氨基]-N-(3-吡啶基甲基)苯甲酰胺

CAS号：289715-28-2

英文名：4-[[7-chloro-3-methyl-2-[(4-methylpiperazin-1-yl)methyl]-4-oxoquinazolin-6-yl]methyl-prop-2-ynylamino]-N-(pyridin-3-ylmethyl)benzamide

分子式

C23H20F3N5O2

熔点

密度

分子量

455.432

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

CB 300919; 4-[[[7-氯-3,4-二氢-3-甲基-2-[(4-甲基-1-哌嗪基)甲基]-4-氧代-6-喹唑啉基]甲基]-2-丙炔-1-基氨基]-N-(3-吡啶基甲基)苯甲酰胺

英文名称

4-[[7-chloro-3-methyl-2-[(4-methylpiperazin-1-yl)methyl]-4-oxoquinazolin-6-yl]methyl-prop-2-ynylamino]-N-(pyridin-3-ylmethyl)benzamide

中文别名

英文别名

4-[N-[7-chloro-3-methyl-2-(4-methyl-piperazin-1-yl)methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]-N-(pyridin-3-ylmethyl)benzamide、CS-0523、4-[N-[7-chloro-3-methyl-2-(4-methyl-piperazin-1-yl)methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]-N-(3-pyridylmethyl)benzamide、UNII-55I8ETE76Y

CAS号

289715-28-2

分子式

C23H20F3N5O2

分子量

455.432

精确质量

455.157

PSA

83.47

LOGP

4.7538

合成路线

3-氨甲基吡啶

3-氨甲基吡啶

tert-butyl 4-[N-[7-chloro-3-methyl-2-(4-methylpiperazin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate

tert-butyl 4-[N-[7-chloro-3-methyl-2-(4-methylpiperazin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate

CB 300919; 4-[[[7-氯-3,4-二氢-3-甲基-2-[(4-甲基-1-哌嗪基)甲基]-4-氧代-6-喹唑啉基]甲基]-2-丙炔-1-基氨基]-N-(3-吡啶基甲基)苯甲酰胺

CB 300919; 4-[[[7-氯-3,4-二氢-3-甲基-2-[(4-甲基-1-哌嗪基)甲基]-4-氧代-6-喹唑啉基]甲基]-2-丙炔-1-基氨基]-N-(3-吡啶基甲基)苯甲酰胺

上游原料

共找到19个上游原料 >

methyl 2-amino-4-chloro-5-methylbenzoate

methyl 2-amino-4-chloro-5-methylbenzoate

tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate

tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate

7-chloro-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

7-chloro-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

tert-butyl 4-[N-[7-chloro-3-methyl-2-(4-methylpiperazin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate

tert-butyl 4-[N-[7-chloro-3-methyl-2-(4-methylpiperazin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate

2-氨基-4-氯-5-甲基苯甲腈

2-氨基-4-氯-5-甲基苯甲腈

2-methoxymethyl-7-chloro-3,6-dimethyl-3,4-dihydroquinazolin-4-one

2-methoxymethyl-7-chloro-3,6-dimethyl-3,4-dihydroquinazolin-4-one

上游原料

methyl 2-amino-4-chloro-5-methylbenzoate tert-butyl 4-[N-[7-chloro-2-hydroxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 7-chloro-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione tert-butyl 4-[N-[7-chloro-3-methyl-2-(4-methylpiperazin-1-ylmethyl)-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate 2-氨基-4-氯-5-甲基苯甲腈 2-methoxymethyl-7-chloro-3,6-dimethyl-3,4-dihydroquinazolin-4-one methyl 2-methoxyacetamido-4-chloro-5-methylbenzoate 2-溴-5-氯-4-甲基苯胺 N-乙酰基-2-溴-5-氯-4-甲基苯胺 2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydro-6-quinazolinyl]methyl}(2-propyn-1-yl)amino]benzoate<wbr 3-氨甲基吡啶 2-氨基-4-氯-5-甲基苯甲酸 [6-(Bromomethyl)-7-chloro-3-methyl-4-oxo-3,4-dihydro-2-quinazolin yl]methyl acetate 3-氯-4-甲基苯胺 (7-Chloro-3,6-dimethyl-4-oxo-3,4-dihydro-2-quinazolinyl)methyl ac etate 3-氟-4-甲基乙酰苯胺 2-acetoxymethyl-7-chloro-6-methyl-3,4-dihydroquinazolin-4-one tert-butyl 4-[N-[7-chloro-2-methanesulfonyloxymethyl-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate