化合物简介
Octreotide (brand name Sandostatin, Novartis Pharmaceuticals) is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. It was first synthesized in 1979 by the chemist Wilfried Bauer.
基本信息
中文名称
奥曲肽
英文名称
acetic acid,10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
中文别名
英文别名
Sandostatin、Sandostatin LAR、Octreotide acetate (USAN)、Octreotide Acetate、Octreotide (acetate)、Sandostatin (TN)、zacycloicosane-4-carboxamide acetate
CAS号
79517-01-4
分子式
C49H66N10O10S2
分子量
1019.24
精确质量
1018.44
PSA
382.82
LOGP
3.021
编号系统
UNII
75R0U2568I
物化性质
外观与性状
无色至灰白色冻干的固体
密度
1.395 g/cm3
沸点
1447.228ºC at 760 mmHg
熔点
153-156ºC
闪点
829.053ºC
储存条件
库房低温,通风,干燥,与食品原料分开存放
安全信息
WGK Germany
3
