卡麦角林_CAS号:81409-90-7_分子式、生产方法、用途、产品-灵元素

化合物简介

Cabergoline (brand names Caberlin, Dostinex and Cabaser), an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. Rat studies show cabergoline has a direct inhibitory effect on pituitary lactotroph (prolactin) cells. It is frequently used as a first-line agent in the management of prolactinomas due to its higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine.

基本信息

中文名称

卡麦角林

英文名称

cabergoline

中文别名

6-烯丙基-N-[3-(二甲基氨基)丙基]-N-(乙基氨基甲酰基)麦角林-8-甲酰胺、1-[(6-Allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)-propyl]-3-ethylurea、-烯丙基-N-[3-(二甲基氨基)丙基]-N-(乙基氨基甲酰基)麦角林-8-甲酰胺、(8Β)-N-[3+(二甲氨基)丙基]-N-[(乙氨基)羧基]-6-(2-丙烯基)麦角林-8-羧酰胺

英文别名

Dostinex(R)、Cabaseril、(6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide、Cabergolina、N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-8g-ergoline-8-carboxamide、Dostinex、Cabergolinum、Cabaser、Cabergolinum [Latin]、Galastop(R)、Galastop、Cabergolina [Spanish]

CAS号

81409-90-7

分子式

C26H37N5O2

分子量

451.604

精确质量

451.295

PSA

71.68

LOGP

3.5227