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2',3'-双脱氧腺苷

2',3'-双脱氧腺苷

CAS号：4097-22-7

英文名：2',3'-Dideoxyadenosine

分子式

C10H13N5O2

熔点

181-184°C(lit.)

密度

1.76 g/cm3

分子量

235.243

沸点

539.1ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

A potent anti-HIV agent.

基本信息

中文名称

2',3'-双脱氧腺苷

英文名称

2',3'-Dideoxyadenosine

中文别名

2\',3\'-二脱氧腺苷、双脱氧腺嘌呤核苷、2,3-二脱氧腺苷、2\',3\'-双脱氧腺甙、二脱氧腺(嘌呤核)苷

英文别名

((2S,5R)-5-(6-Amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methanol、9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine、[(2S,5R)-5-(6-aminopurin-9-yl)oxolan-2-yl]methanol、Dideoxyadenosine、9-(2,3-Dideoxy-β-D-ribofuranosyl)adenine、Didanosine impurity G

CAS号

4097-22-7

分子式

C10H13N5O2

分子量

235.243

精确质量

235.107

PSA

99.08

LOGP

0.6596

编号系统

UNII

4Q86AH641A

物化性质

外观与性状

白色结晶粉末

密度

1.76 g/cm3

沸点

539.1ºC at 760 mmHg

熔点

181-184°C(lit.)

折射率

-34 ° (C=1, H2O)

储存条件

2-8ºC

安全信息

RTECS号

AU7358900

安全说明

S26; S27; S36/37/39; S45

WGK Germany

2

危险类别码

R34

海关编码

2934999090

危险品标志

C

生产方法及用途

用途

用作抗病毒药。

合成路线

共找到4条合成路线 >

2,3-二脱氧-2,3-二氢腺苷

2,3-二脱氧-2,3-二氢腺苷

2',3'-双脱氧腺苷

2',3'-双脱氧腺苷

上游原料

共找到44个上游原料 >

2,3-二脱氧-2,3-二氢腺苷

2,3-二脱氧-2,3-二氢腺苷

O-((2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((tert-butyldiphenylsilyl)oxy)methyl)tetrahydrofuran-3-yl) 1H-imidazole-1-carbothioate

O-((2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((tert-butyldiphenylsilyl)oxy)methyl)tetrahydrofuran-3-yl) 1H-imidazole-1-carbothioate

((2S)-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl benzoate

((2S)-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl benzoate

((2S,5R)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl pivalate

((2S,5R)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl pivalate

2-Furanmethanol, 5-(acetyloxy)tetrahydro-, benzoate, (2S-trans)-

2-Furanmethanol, 5-(acetyloxy)tetrahydro-, benzoate, (2S-trans)-

下游产品

共找到4个下游商品 >

2',3'-双脱氧腺苷

2',3'-双脱氧腺苷

[(2S,5R)-5-purin-9-yloxolan-2-yl]methanol

[(2S,5R)-5-purin-9-yloxolan-2-yl]methanol

[(2S,5R)-5-(6-amino-8-bromopurin-9-yl)oxolan-2-yl]methanol

[(2S,5R)-5-(6-amino-8-bromopurin-9-yl)oxolan-2-yl]methanol

地丹诺辛

上游原料

2,3-二脱氧-2,3-二氢腺苷 O-((2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((tert-butyldiphenylsilyl)oxy)methyl)tetrahydrofuran-3-yl) 1H-imidazole-1-carbothioate 腺苷 ((2S)-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl benzoate ((2S,5R)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl pivalate D-2',3'-O-thiocarbonylene-5'-O-tert-butyldimethylsilyl adenosine 6-aminopurine ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-((methoxycarbonothioyl)oxy)tetrahydrofuran-2-yl)methyl acetate [5-(6-amino-purin-9-yl)-4,5-dihydro-furan-2-yl]-methanol (2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl dimethanesulfonate 1-O-acetyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2-(phenylselenenyl)-D-erythro-pentafuranose 9-(2'-O-Acetyl-3'-bromo-3'-deoxy-β-D-xylofuranosyl)adenine 5'-O-formyladenosine 9-[2,5-bis-O-(tert-butyldimethylsilyl)-3-deoxy-β-D-ribofuranosyl]adenine 5-(羟基甲基)二氢-2(3H)-呋喃酮 (S)-5-(benzoyloxymethyl)tetrahydrofuran-2-one (S)-5-羟甲基二氢呋喃-2-酮 9-(5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pentofuranosyl)adenine 2’,3’-二脱氧尿苷 9-(2-O-acetyl-3-bromo-3-deoxy-5-O-(2,4,4-trimethyl-5-oxo-1,3-dioxolan-2-yl)-β-D-xylofuranosyl)adenine 2’-脱氧腺苷 5'-O-acetyl-2'-deoxyadenosine 5'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine (2S)-2-((benzyloxy)methyl)-5-bromotetrahydrofuran (S)-(5-oxotetrahydrofuran-2-yl)methyl pivalate O-((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-((tert-butyldimethylsilyl)oxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-3-yl) 1H-imidazole-1-carbothioate 2',3'-双脱氧腺苷 5'-O-(tert-butyldimethylsilyl)-2',3'-bis-O-[(methylthio)-thiocarbonyl]adenosine 5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-D-erythro-pentonic acid γ-lactone (2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((tert-butyldiphenylsilyl)oxy)methyl)tetrahydrofuran-3-ol 虫草素 5'-O-[(1,1-dimethylethyl)dimethylsilyl]2',3'-didehydro-2',3'-dideoxyadenosine Adenosine, 2'-deoxy-, 5'-benzoate (S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-trimethylsilanyloxy-2,3-dihydro-furan 9-<5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl>adenine 6-chloro-9-[5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl]-9H-purine

下游产品

2',3'-双脱氧腺苷 [(2S,5R)-5-purin-9-yloxolan-2-yl]methanol [(2S,5R)-5-(6-amino-8-bromopurin-9-yl)oxolan-2-yl]methanol 地丹诺辛