化合物简介
Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong growth inhibition.
基本信息
中文名称
印苦楝内酯
英文名称
Nimbolide
中文别名
英文别名
(4S,4aS,8aS)-4-(tert-Butyl-dimethylsilyl)oxy-?7,7-dimethoxy-4a-methyl-3,4,5,6,8,8a-?hexahydro-2H-naphthalen-1-one、(4S,4aS,8aS)-4-(dimethyl-tert-butyl-silyl)oxy-7,7-dimethoxy-4a-methyl-decalin-1-one
CAS号
25990-37-8
分子式
C27H30O7
分子量
466.523
精确质量
466.199
PSA
92.04
LOGP
3.599
物化性质
密度
1.32g/cm3
沸点
608.6ºC at 760 mmHg
闪点
321.9ºC
折射率
1.596
蒸汽压
9.34E-15mmHg at 25°C
