化合物简介
Ibrutinib (USAN, also known as PCI-32765 and marketed under the name Imbruvica) is an anticancer drug targeting B-cell malignancies. It is an orally-administered, selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase (BTK).
基本信息
中文名称
依鲁替尼
英文名称
ibrutinib
中文别名
英文别名
2-Propen-1-one, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-
CAS号
936563-96-1
分子式
C25H24N6O2
分子量
440.497
精确质量
440.196
PSA
99.16
LOGP
4.7364
编号系统
MDL号
MFCD20261150