化合物简介
EPPTB is a selective antagonist of the trace amine-associated 1 (TA1) receptor, increasing the firing frequency of dopamine (DA) neurons in the ventral tegmental area. This makes it a promising drug target for neurodegenerative disorders.
基本信息
中文名称
N-(3-ethoxy-phenyl)-4-pyrrolidin-1-yl-3-trifluoromethylbenzamide
英文名称
N-(3-ethoxy-phenyl)-4-pyrrolidin-1-yl-3-trifluoromethylbenzamide
中文别名
英文别名
EPPTB、RO5212773、BENZAMIDE, N-(3-ETHOXYPHENYL)-4-(1-PYRROLIDINYL)-3-(TRIFLUOROMETHYL)-、N-(3-ethoxy-phenyl)-4-pyrrolidin-1-yl-3-trifluoromethyl-benzamide
CAS号
1110781-88-8
分子式
C20H21F3N2O2
分子量
378.388
精确质量
378.156
PSA
41.57
LOGP
5.0946
