化合物简介
Pipequaline (INN) (developmental code name PK-8165) is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.
基本信息
中文名称
哌夸林
英文名称
2-phenyl-4-(2-piperidin-4-ylethyl)quinoline
中文别名
英文别名
Pipequalina、Pipequalina [Spanish]、Pipequalinum [Latin]、Quinoline,2-phenyl-4-(2-(4-piperidinyl)ethyl)、2-Phenyl-4-(2-(4-piperidyl)ethyl)quinoline、2-phenyl-4-[2-(piperidin-4-yl)ethyl]quinoline、Pipequalinum、PK-8165、Pipequaline
CAS号
77472-98-1
分子式
C22H24N2
分子量
316.439
精确质量
316.194
PSA
24.92
LOGP
5.1628
编号系统
UNII
J3S205V4I2
物化性质
密度
1.078g/cm3
沸点
489.2ºC at 760 mmHg
闪点
249.7ºC
折射率
1.602
