化合物简介
PD-128,907 is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D2 and D3 receptors. It is used for studying the role of these receptors in the brain, in roles such as inhibitory autoreceptors that act to limit further dopamine release, as well as release of other neurotransmitters. In animal studies it has been shown to reduce toxicity from cocaine overdose.
基本信息
中文名称
(+)-PD 128907, 盐酸盐
英文名称
(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol, hydrochloride
中文别名
(4AR,10AR)-1-丙基-2,3,10,10A-四氢-1H,4AH-4,9-二氧杂-1-氮杂菲-6-醇盐酸盐、(+)-PD 128,907盐酸盐
英文别名
(+)-PD128907、(4aR,10bR)-rel-4-Propyl-2,3,4,4a,5,10b-hexahydrochromeno[4,3-b][1,4]oxazin-9-ol
CAS号
300576-59-4
分子式
C14H20ClNO3
分子量
285.767
精确质量
285.113
PSA
41.93
LOGP
2.6764
物化性质
沸点
389ºC at 760mmHg
闪点
189ºC