化合物简介
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
基本信息
中文名称
二油酰基 L-α-磷脂酰乙醇胺
英文名称
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
中文别名
1,2-二油酰-sn-甘油-3-磷酸乙醇胺、1,2-二油锡甘油-3-磷酸乙醇胺
英文别名
1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine、DIOLEOYL PHOSPHATIDYL ETHANOLAMINE、1,2-di-O-oleoyl-sn-glycero-3-phosphatidylethanolamine、COATSOME ME-8181 (DOPE)、Dioleoyl phosphoethanolamine、18:1 PE、1,2-dioleoyl-sn-glycerol-3-phosphoethanolamine、3-SN-PHOSPHATIDYLETHANOLAMINE,1,2-DIDEOYL、DOPE、L-A-phosphatidylethanolamine dioleoyl、1,2-dioleoyl-sn-glycero-3-phosphoethanoloamine、1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)
CAS号
4004-05-1
分子式
C41H78NO8P
分子量
744.034
精确质量
743.547
PSA
144.19
LOGP
12.309
编号系统
UNII
JNP6V6AI0U
物化性质
外观与性状
冻干的粉末
密度
1.008g/cm3
沸点
759.221ºC at 760 mmHg
闪点
412.962ºC
折射率
1.484
储存条件
-20ºC
蒸汽压
0mmHg at 25°C
安全信息
安全说明
36/37
危险类别码
R22; R38; R40; R48/20/22
危险品运输编码
UN 1888
海关编码
2931900090
危险品标志
Xn
危险性描述
H302; H315; H319; H331; H336; H351; H361d; H372
信号词
Danger
危险性防范说明
P261; P281; P305 + P351 + P338; P311
危险标志
GHS06, GHS08
上游原料
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