化合物简介
Segesterone acetate (USAN) (brand name Nestorone; former developmental code names ST-1435, AC-6844, CS-0411), known more commonly simply as nestorone (or nestoron) and also known as elcometrine, is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. Nestorone is the acetate ester of segesterone, which was never marketed, but is an active metabolite of nestorone. Nestorone is only weakly active orally, and is instead given as a subcutaneous implant. It is more than 100-fold times as potent when delivered subcutaneously relative to orally.
基本信息
中文名称
醋酸烯诺孕酮
英文名称
Nestoron
中文别名
英文别名
19-Norpregn-4-ene-3,20-dione,17-hydroxy-16-methylene-,acetate、NESTORONE、17-(ACETYLOXY)-16-METHYLENE-19-NORPREGN-4-ENE-20-DIONE、16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate、Elcometrine、17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate
CAS号
7759-35-5
分子式
C23H30O4
分子量
370.482
精确质量
370.214
PSA
60.44
LOGP
4.1852
编号系统
UNII
9AMX4Q13CC
物化性质
密度
1.15g/cm3
沸点
499.3ºC at 760mmHg
闪点
216.2ºC
折射率
1.549