化合物简介
Lurtotecan is a semi-synthetic analog of camptothecin with antineoplastic activity. Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued.
基本信息
中文名称
勒托替康
英文名称
Lurtotecan
中文别名
英文别名
11H-1,4-Dioxino(2,3-g)pyrano(3\',4\':6,7)indolizino(1,2-b)quinoline-9,12(8H,14H)-dione,8-ethyl-2,3-dihydro-8-hydroxy-15-((4-methyl-1-piperazinyl)methyl)-,(8S)、GG 211、NX 211、(7-(4-methylpiperazinomethylene)-10,11-ethylenedioxy-20(S)-camptothecin)、OSI-211、7-[(4-methylpiperazino)methyl]-10,11-(ethylenedioxy)-(20S)-camptothecin
CAS号
149882-10-0
分子式
C28H30N4O6
分子量
518.561
精确质量
518.217
PSA
106.36
LOGP
1.474
编号系统
UNII
4J1L80T08I
物化性质
密度
1.5g/cm3
沸点
844.8ºC at 760mmHg
闪点
464.7ºC
折射率
1.73
蒸汽压
2.51E-30mmHg at 25°C
